Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2003-01-08
2009-11-10
Schultz, J D (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C536S024300, C435S091200
Reexamination Certificate
active
07615341
ABSTRACT:
An gene was identified as a RA disease susceptibility gene on Human Chromosome 8, the gene coding a protein that has an amino acid sequence shown in SEQ. ID NO. 1 and that has such mutation that glycine is inserted as a 269th amino acid in the sequence. Moreover, it was found that mutation of the gene and the protein relate to onset of RA. Achieved is a method of evaluating with high accuracy the onset or onset possibility of RA by using the mutation.
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Komai Koichiro
Nakatsukasa Mikiko
Shiozawa Shunichi
Conlin David G.
Edwards Angell Palmer & & Dodge LLP
Pohnert Steven C
Russett Mark D.
Schultz J D
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