Titania-based coating for capillary microextraction

Details Titania-based coating for capillary microextraction Titania-based coating for capillary microextraction

2005-07-19

2009-11-24

Speer, Timothy M (Department: 1794)

Stock material or miscellaneous articles

Composite

Of quartz or glass

C438S446000, C438S450000, C438S701000, C438S702000

Reexamination Certificate

active

07622191

ABSTRACT:
A method is presented describing in situ preparation of the titania-based sol-gel PDMS coating and its immobilization on the inner surface of a fused silica microextraction capillary. Sol-gel titania-poly (dimethylsiloxane) (TiO2-PDMS) coating was developed for capillary microextraction (CME) to perform on-line preconcentration and HPLC analysis of trace impurities in aqueous samples. The sol-gel titania-based coatings demonstrated strong pH stability and enhanced extraction capability over other commercially availble GC coatings. Extraction characteristics of a sol-gel titania-PDMS capillary remained practically unchanged after continuous rinsing with a 0.1 M NaOH solution (pH=13) for 12 hours.

REFERENCES:
patent: 4509964 (1985-04-01), Hubball et al.
patent: 4966785 (1990-10-01), Springston
patent: 5128291 (1992-07-01), Wax et al.
patent: 5192406 (1993-03-01), Woolley
patent: 5262052 (1993-11-01), Rossiter et al.
patent: 5270027 (1993-12-01), Balducci et al.
patent: 5308495 (1994-05-01), Avnir et al.
patent: 5589396 (1996-12-01), Frye et al.
patent: 5624875 (1997-04-01), Nakanishi et al.
patent: 5637135 (1997-06-01), Ottenstein et al.
patent: 5821186 (1998-10-01), Collins
patent: 5869152 (1999-02-01), Colon
patent: 6344242 (2002-02-01), Stolk et al.
patent: 6613234 (2003-09-01), Voute et al.
patent: 6759126 (2004-07-01), Malik et al.
patent: 6783680 (2004-08-01), Malik
patent: 2003/0075447 (2003-04-01), Malik et al.
patent: 2004/0129141 (2004-07-01), Malik et al.
patent: 2005/0106068 (2005-05-01), Malik et al.
patent: WO 00/11463 (2000-03-01), None
Zeng, Z. et al. “Solid-Phase Microextraction Using Fused-Silica Fibers Coated with Sol-Gel-Derived Hydroxy-Crown Ether”,Anal. Chem., 73, 2429-2436 (2001).
Zhang, J. et al. “Development of the Personal Aldehydes and Ketones Sampler Based upon DNSH Derivatization on Solid Sorbent”,Environ. Sci. Technol., 34, 2601-2607 (2000).
Zhang, Z. et al. “Solid-Phase Microextraction”,Anal. Chem. 66, 844A-853A (1994).
U.S. Appl. No. 10/704,766, filed Nov. 10, 2003, Malik et al.
Aichholz, R., “Preparation of Glass Capillary Columns Coated with OH-Terminated (3,3,3-Trifluoropropyl) Methyl Polysiloxane (PS 184.5)”,Journal of High Resolution Chromatography, 13, 71-73 (1990).
Albin, M. et al. “Sensitivity Enhancement for Capillary Electrophoresis”,Analytical Chemistry, 65, 489-497A (1993).
Alltech,Chromatography Catalog, 172 (1997).
Altgelt, K. et al.,Chromatography in Petroleum Analysis, Marcel Dekker, Inc., New York and Basel (1979).
Alhooshani, K. et al. “Sol-Gel Approach to in situ Creation of High pH-resistant surface-bonded Organic-Inorganic Hybrid Zirconia Coating for Capillary Microextraction (in-tube SPME)”Journal of Chromatography A, 1065, 1-14 (2005).
Belardi, R. et al., “The Application of Chemically Modified Fused Silica Fibers in the Extraction of Organics from Water Matrix Samples and their Rapid Transfer to Capillary Columns”,Water Pollut. Res. J. Can., 24, 179-191 (1989).
Berezkin, V.G. et al., “Capillary Columns with Several Layers of Different Immobilized Stationary Phases”,J. Anal. Chem.—USSR, 47, 600-604 (1992).
Berezkin, V.G. et al.,Gas Chromatography in Air Pollution Analysis, Elsevier, Amsterdam—Oxford—New York—Tokyo, Chapter 8, 165-207 (1991).
Bigham, S. et al. “Sol-Gel Capillary Microextraction”,Anal. Chem. 74, 752-761 (2002).
Blau, K. et al., eds.,Handbook of Derivatives for Chromatography, 2nded., John Wiley & Sons, Chichester—New York—Brisbane—Toronto—Singapore, 1-30 (1993).
Blomberg, L. et al., “Modification of Glass Capillary Columns by Cyclic (3,3,3-Trifluoropropyl)methylsiloxanes”,Journal of HRC&CC, 3, 527-528 (1980).
Brinker, C.J. et al.,Sol-Gel Science: The Physics and Chemistry of Sol-Gel Processing, Academic Press, San Diego—New York—Boston—London—Sydney—Tokyo—Toronto, 97-233 (1990).
Britz-McKibbin, P. et al. “On-Line Focusing of Flavin Derivative Using Dynamic pH Junction-Sweeping Capillary Electrophoresis with Laser-Induced Fluorescence Detection”,Anal. Chem., 74, 3736-3743 (2002).
Britz-McKibbin, P. et al. “Selective Focusing of Catecholamines and Weakly Acidic Compounds by Capillary Electrophoresis Using a Dynamic pH Junction”,Anal. Chem., 72, 1242-1252 (2000).
Brown, P. B. et al. “The Separation and the Characterization of Long Chain Fatty Acids and Their Derivatives by Reversed Phase High Performance Liquid Chromatography”,Analytical Chemistry, 21, 193-208, (1989).
Cao, C.-X. et al. “Stacking Ionizable Analytes in a Sample Matrix with High Salt by a Transient Moving Chemical Reaction Boundary Method in Capillary Zone Electrophoresis”,Anal. Chem. 74, 4167-4174 (2002).
Chen, Z. et al. “Chemically Modified chiral monolithic Silica Column Prepared by a Sol-Gel Process for Enantiomeric Separation by Micro High-Performanc Liquid Chromatography”,J. Chromatogra., 942, 83-91 (2002).
Chien, R.-L. et al. “On-Column Sample Concentration Using Field Amplification in CZE”,Anal. Chem., 64, 489A-496A (1992).
Chien, R.-L et al. “Sample Stacking of an Extremely Large Injection Volume in High-Performance Capillary Electrophoresis”,Anal. Chem., 64, 1046-1050 (1992).
Chun, M.-S. et al. “Protein Analysis with Large Volume Sample Stacking with an Electrosmotic Flow Pump: A Potential Approach for Proteomics”,Microchem. J., 70, 247-253 (2001).
Church, M. N. et al. “Transient Isotachophoretic-Electrophoretic Separations of Lanthanides with Indirect Laser-Induced Fluorescence Detection”,Anal. Chem., 70, 2475-2480 (1998).
Cifuentes, A. et al. “Capillary Isoelectric Focusing of Erythropoietin Glycoforms and its Comparison with Flat-bed Isoelectric Focusing and Capillary Zone Electrophoresis”,J. Chromatogra., 830, 453-463 (1999).
Clarke, N. J. et al. “Capillary Isoelectric Focusing-Mass Spectrometry: Analysis of Protein Mixtures from Human Body Fluids”,Biomed. Chromatogr., 16, 287-297 (2002).
Clifford, A. A. “Introduction to Supercritical Fluid Extraction in Analytical Science”, inSupercritical Fluid Extraction and its Use in Chromatographic Sample Preparation, Westwood, S. A. (ed.), 1-38 (1993).
Collinson, M. M. et al. “Sol-gels and Electochemistry”,Analytical Chemistry, 72, 702A-709A (2000).
Coulibaly, K. et al. “An overview of Solid-Phase Extraction of Food Flavor Compounds and Chemical Residues”,Food Rev. Int., 12, 131-151 (1996).
Deng, Y. et al. “Chip-Based Quantitative Capillary Electrophoresis/Mass Spectrometry Determination of Drugs in Human Plasma”,Anal. Chem., 73, 1432-1439 (2001).
Ettre, L.S. et al.,Basic Relationships of Gas Chromatography, Advanstar, Cleveland, OH, 1-34 (1993).
Ettre, L.S., “Performance of Open Tubular Columns as a Function of Tube Diameter and Liquid Phase Film Thickness”,Chromatographia, 18, 477-488(1984).
Ferioli, V. et al., “High-Performance Liquid Chromatography of Dihydroxyacetone as its bis-2,4-Dinitrophenylhydrazone Derivative,”Chromatographia, 41, 61-65 (1995).
Furton, K. G. et al. “The Use of Solid-Phase Microextraction-Gas Chromatography in Forensic Analysis”,Journal of Chromatographic Science, 38, 297-306, (2000).
Guo, Y. et al. “A Stationary Phase for Open Tubular Liquid Chromatography and Electrochromatography Using Sol-Gel Technology”,Anal. Chem., 67, 2511-2516 (1995).
Hamlet, C. et al., “Novel Sol-Gel Dendrimer Coatings for Ultra-Trace Environmental Analysis by Capillary Microextraction Coupled to Gas Chromatography”,5thInternational Symposium on Advances in Extraction Technologies, St. Pete Beach, FL (Mar. 5-7, 2003).
Hartmann, H. et al., “Trace Determination of Pesticides in Water by Coated Capillary Micro Extraction (CCME) and Reversed-Phase High Performance Liquid

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