Micro fluidic gas assisted ionization device and method

Radiant energy – Ionic separation or analysis – With sample supply means

Reexamination Certificate

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C250S281000, C250S282000

Reexamination Certificate

active

07495210

ABSTRACT:
The invention provides a mass spectrometry system, including a microfluidic chip for electrospray ionization having an analyte channel and a gas assist channel that define a spray tip and a detector downstream from the microfluidic chip for detecting ions.The invention also provides a micro fluidic chip for electrospray ionization including a substrate having an analyte channel, a gas channel and an analyte channel wherein the gas channel and analyte channel exit at the first end to define the electrospray tip.Methods of using the system and apparatus are also disclosed.

REFERENCES:
patent: 7070682 (2006-07-01), Lee et al.
patent: 2003/0026740 (2003-02-01), Staats
patent: 2006/0027744 (2006-02-01), Stults et al.
patent: 2006/0060769 (2006-03-01), Bousse et al.
patent: 2006/0242832 (2006-11-01), Weng et al.
patent: 97/04297 (1997-02-01), None
patent: 00/41214 (2000-07-01), None
patent: 2004/051697 (2004-06-01), None
patent: 2005/019804 (2005-03-01), None
UK Intellectual Property Office, Patents Act: 1977 Search Report under Section 17, Aug. 15, 2007.

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