Indoline derivatives substituted in the 6-position, their...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S397000, C514S414000, C514S418000, C544S373000, C548S312100, C548S465000

Reexamination Certificate

active

07547703

ABSTRACT:
The present invention relates to indolinone derivatives, substituted in the 6-position, of the formulain whichR1to R6and X are as defined in claim1, to their tautomers, enantiomers, diastereomers, to their mixtures and to their salts, in particular their physiologically acceptable salts, which have useful pharmacological properties, in particular in inhibiting action on various receptor tyrosine kinases and on the proliferation of endothelial cells and various tumour cells, to medicaments comprising these compounds, to their use and to processes for their preparation.

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