Method and apparatus for the automated generation of nucleic...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

Reexamination Certificate

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C435S006120, C435S091100, C536S023100, C536S024300, C536S025400

Reexamination Certificate

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07629151

ABSTRACT:
The present invention includes a method and device for performing automated SELEX. The steps of the SELEX process are performed at one or more work stations on a work surface by a robotic manipulator controlled by a computer. The invention also includes methods and reagents to obviate the need for size-fractionation of amplified candidate nucleic acids before beginning the next round of the SELEX process.

REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4753983 (1988-06-01), Ngo
patent: 5158871 (1992-10-01), Rossomando et al.
patent: 5270163 (1993-12-01), Gold et al.
patent: 5443791 (1995-08-01), Cathcart et al.
patent: 5472841 (1995-12-01), Jayasena et al.
patent: 5475096 (1995-12-01), Gold et al.
patent: 5476766 (1995-12-01), Gold et al.
patent: 5496938 (1996-03-01), Gold et al.
patent: 5503978 (1996-04-01), Schneider et al.
patent: 5567588 (1996-10-01), Gold et al.
patent: 5580737 (1996-12-01), Polisky et al.
patent: 5610287 (1997-03-01), Nikiforov et al.
patent: 5620850 (1997-04-01), Bamdad et al.
patent: 5637459 (1997-06-01), Burke et al.
patent: 5656493 (1997-08-01), Mullis et al.
patent: 5660985 (1997-08-01), Pieken et al.
patent: 5683867 (1997-11-01), Biesecker et al.
patent: 5705337 (1998-01-01), Gold et al.
patent: 5707796 (1998-01-01), Gold et al.
patent: 5723323 (1998-03-01), Kauffman et al.
patent: 5737498 (1998-04-01), Murray
patent: 5761177 (1998-06-01), Muneyoshi et al.
patent: 5763177 (1998-06-01), Gold et al.
patent: 5780228 (1998-07-01), Parma et al.
patent: 5843653 (1998-12-01), Tuerk et al.
patent: 5861254 (1999-01-01), Schneider et al.
patent: 5866336 (1999-02-01), Nazarenko et al.
patent: 5955268 (1999-09-01), Granados et al.
patent: 5985548 (1999-11-01), Collier et al.
patent: 6001577 (1999-12-01), Gold et al.
patent: 6011020 (2000-01-01), Gold et al.
patent: 6114120 (2000-09-01), Jensen et al.
patent: 6235471 (2001-05-01), Knapp et al.
patent: 6291184 (2001-09-01), Gold et al.
patent: 6376190 (2002-04-01), Gold et al.
patent: 6387620 (2002-05-01), Smith et al.
patent: 6458539 (2002-10-01), Gold et al.
patent: 6569620 (2003-05-01), Gold et al.
patent: 6716580 (2004-04-01), Gold et al.
patent: 6716583 (2004-04-01), Gold et al.
patent: 2002/0064780 (2002-05-01), Gold et al.
patent: 0 236 069 (1987-09-01), None
patent: 2 183 661 (1987-06-01), None
patent: WO 89/06694 (1989-07-01), None
patent: WO 91/19813 (1991-12-01), None
patent: WO 92/06380 (1992-04-01), None
patent: WO 92/14843 (1992-09-01), None
patent: WO 93/05182 (1993-03-01), None
patent: WO 95/08003 (1995-03-01), None
patent: WO 96/34874 (1995-03-01), None
patent: WO 98/33941 (1998-08-01), None
Padgett KA et al ‘Creating seamless junctions independent of restriction sites in PCR cloning.’ Gene. Feb. 2, 1996;168(1):31-5.
Crameri A et al ‘10(20)-fold aptamer library amplification without gel purification.’ Nucleic Acids Res. Sep. 11, 1993;21(18):4410.
Shuber A.P. et al ‘A simplified procedure for developing multiplex PCRs.’ Genome Res. Dec. 1995;5(5):488-93.
Chae K.-S. et al ‘The use of overlapping and tailed short primers in the chromosomal assignment of short cDNAs by the polymerase chain reaction.’ Gene. May 16, 1994;142(2):199-205.
Breslauer K.J. ‘Predicting DNA duplex stability from the base sequence’ Proc. Natl. Acad. Sci USA, vol. 83, pp. 3746-3750.
Cheskis and Freedman (1996) Biochemistry, 35:3309-3318.
Cox et al. (1998) Biotechn. Prog. 14:845-850.
Cox & Ellington (2001) Bioorganic & Medical Chemistry 9:2525.
Crameri & Stemmer (1993)Nucleic Acids Research21:4410.
Ellington and Szostak, (1990) p. 84, Abstract Presented at Cold Spring Harbor RNA Processing Meeting, May 16-20, 1990, Selection of RNAs with Ligand-Specific Binding Activity from Pools of Random Sequence.
Fisher et al., (1994)Protein Science, 3:257-266.
Hanna (1989)Methods in Enzymology180:383.
Heid, et al. (1996)Genome Res.6:986.
Joyce (1989) Gene 82:83.
Joyce and Inoue (1989) Nucleic Acids Research 17:711.
Karlsson (1994) Analytical Biochemistry 221:142-151.
Karlsson (1991) J. of Immunological Methods 145:229.
Kinzler and Vogelstein (1989) Nucleic Acids Research 17:3645.
Kramer (1974) J. Mol. Biol. 89:719.
Levisohn and Spiegleman (1968) Proc. Natl. Acad. Sci. USA 60:866-872.
Levisohn and Spiegleman (1969) Proc. Natl. Acad. Sci. USA 63:805-811.
Mitsuhashi, Technical Report: Part 2. Basic Requirements for Designing Optimal PCT Primers. J. of Clinical Lab. Anal. 10(5): 285-293. (1996).
Oliphant et al.(1989) Mol. Cell. Biol. 9:2944.
Oliphant and Struhl (1988) Nucleic Acids Research 16:7673-7683.
Oliphant and Struhl (1987) Methods in Enzymology 155:568-582.
Oliphant et al. (1986) Gene 44:177-183, Nussbaum & Strul.
Robertson and Joyce (1990) Nature 344:467.
Sooter, et al.(2001) Biol. Chem. 382:1327.
Szostak (1988)Redesigning the Molecules of Life, (S.A. Benner ed.) Springer-Verlag Berlin Heidelberg, pp. 87-113.
Thiesen and Bach (1990) Nucleic Acids Res. 18:3203.
U.S. Appl. No. 60/278,354, filed Mar. 22, 2001, Smith et al.
Marshall & Ellington (Nov. 1999) J. Mol. Evol. 49:656-663, Molecular Parasites that Evolve Longer Genomes.
Schneeberger, et al., (1995) PCR Meth. Appl. 4:234-238, Quantitative Detection of Reverse Transcriptase-PCR Products by Means of a Novel and Sensitive DNA Stain.

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