Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-05-07
2009-02-10
Jiang, Shaojia Anna (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07488829
ABSTRACT:
Compounds of the formula I,in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
REFERENCES:
patent: 5656624 (1997-08-01), Vaccaro et al.
patent: 5756470 (1998-05-01), Yumibe et al.
patent: 5846966 (1998-12-01), Rosenblum et al.
patent: 5889002 (1999-03-01), Nielsen et al.
patent: 6225310 (2001-05-01), Nielsen et al.
patent: 6268343 (2001-07-01), Knudsen et al.
patent: 6992067 (2006-01-01), Glombik et al.
patent: WO 97/16455 (1997-05-01), None
patent: WO 97/26265 (1997-07-01), None
patent: WO 97/41097 (1997-11-01), None
patent: WO 97/45406 (1997-12-01), None
patent: WO 98/08871 (1998-03-01), None
patent: WO 99/03861 (1999-01-01), None
patent: WO 00/63703 (2000-10-01), None
Castañer, R.M., et al., “Ezetimbe, Hypolipidemic Cholesterol Absorption Inhibitor SCH-58235,” Drugs of the Future 2000, 25(7):679-685.
Goodman and Gilman's “The Pharmacological Basis of Therapeutics”, 10thEd., 1996, p. 54.
Vaccaro, Wayne D., et al., “Sugar-Substituted 2-Azetidinone As Cholesterol Absorption Inhibitors,” Bioorganic & Medicinal Chemistry Letters 8(1998):35-40.
Vaccaro, Wayne D., et al., “Sugar-Substituted 2-Azetidinone Cholesterol Absorption Inhibitors: Enhanced Potency by Modification of the Sugar,” Bioorganic & Medicinal Chemistry Letters 8(1998):313-318.
van Heck, Margaret et.al., Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663, British Journal of Pharmacology 129:1748-1754 (2000).
Zaks, Aleksey, et al., Enzymatic Glucuronidation of a Novel Cholesterol Absorption Inhibitor, SCH 58235, Applied Biochemistry and Biotechnology, 73:205-213 (1998).
Flohr Stefanie
Frick Wendelin
Glombik Heiner
Heuer Hubert
Jaehne Gerhard
Finnegan Henderson Farabow Garrett & Dunner LLP
Jiang Shaojia Anna
Krishnan Ganapathy
Sanofi-Aventis Deutschland GmbH
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