Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2007-03-20
2009-10-20
Weber, Jon P (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S350000, C530S402000, C514S002600, C514S054000, C514S059000, C525S054100, C525S054110, C525S054200
Reexamination Certificate
active
07605232
ABSTRACT:
A method of concentrating proteins from whole blood comprising exposing whole blood to covalently crosslinked hydrogel to remove water from the blood into the hydrogel to thereby concentrate the proteins in the whole blood. The hydrogel may absorb, for example, 50% or 90% of the water from the blood while excluding proteins with a weight of more than about 15,000 Daltons. In some embodiment, the hydrogels are dry, sterile, and spherical.
REFERENCES:
patent: 2533004 (1950-12-01), Ferry et al.
patent: 3520949 (1970-07-01), Shepard et al.
patent: 4101380 (1978-07-01), Rubinstein et al.
patent: 4359049 (1982-11-01), Redl et al.
patent: 4362567 (1982-12-01), Schwarz et al.
patent: 4414976 (1983-11-01), Schwarz et al.
patent: 4565784 (1986-01-01), Franzblau et al.
patent: 4601286 (1986-07-01), Kaufman
patent: 4631055 (1986-12-01), Redl et al.
patent: 4646730 (1987-03-01), Schonfeld et al.
patent: 4670417 (1987-06-01), Iwasaki et al.
patent: 4735616 (1988-04-01), Eibl et al.
patent: 4874368 (1989-10-01), Miller et al.
patent: 4902281 (1990-02-01), Avoy
patent: 4909251 (1990-03-01), Seelich
patent: 4932942 (1990-06-01), Maslanka
patent: 4937270 (1990-06-01), Hamilton et al.
patent: 4938763 (1990-07-01), Dunn
patent: 4978336 (1990-12-01), Capozzi et al.
patent: 5024742 (1991-06-01), Nesburn et al.
patent: 5030215 (1991-07-01), Morse et al.
patent: 5041292 (1991-08-01), Feijen
patent: 5104909 (1992-04-01), Grasel
patent: 5116315 (1992-05-01), Capozzi et al.
patent: 5143662 (1992-09-01), Chesterfield et al.
patent: 5162430 (1992-11-01), Rhee et al.
patent: 5192743 (1993-03-01), Hsu et al.
patent: 5292362 (1994-03-01), Bass et al.
patent: 5296518 (1994-03-01), Grasel
patent: 5304595 (1994-04-01), Rhee et al.
patent: 5318524 (1994-06-01), Morse et al.
patent: 5324775 (1994-06-01), Rhee et al.
patent: 5328955 (1994-07-01), Rhee et al.
patent: 5368563 (1994-11-01), Lonneman et al.
patent: 5395923 (1995-03-01), Bui-Khac et al.
patent: 5399351 (1995-03-01), Leshchiner et al.
patent: 5405607 (1995-04-01), Epstein
patent: 5410016 (1995-04-01), Hubbell et al.
patent: 5413791 (1995-05-01), Rhee et al.
patent: 5419491 (1995-05-01), Breitsprecher
patent: 5426148 (1995-06-01), Tucker
patent: 5446090 (1995-08-01), Harris
patent: 5446091 (1995-08-01), Rhee et al.
patent: 5455027 (1995-10-01), Zalipsky et al.
patent: 5470911 (1995-11-01), Rhee et al.
patent: 5474540 (1995-12-01), Miller et al.
patent: 5475052 (1995-12-01), Rhee et al.
patent: 5476909 (1995-12-01), Kim et al.
patent: 5505704 (1996-04-01), Pawelka et al.
patent: 5514379 (1996-05-01), Weissleder et al.
patent: 5514380 (1996-05-01), Song et al.
patent: 5527856 (1996-06-01), Rhee et al.
patent: 5529914 (1996-06-01), Hubbell et al.
patent: 5550187 (1996-08-01), Rhee et al.
patent: 5565519 (1996-10-01), Rhee et al.
patent: 5567435 (1996-10-01), Hubbell et al.
patent: 5573934 (1996-11-01), Hubbell et al.
patent: 5582596 (1996-12-01), Fukunaga et al.
patent: 5583114 (1996-12-01), Barrows
patent: 5605541 (1997-02-01), Holm
patent: 5614587 (1997-03-01), Rhee et al.
patent: 5626863 (1997-05-01), Hubbell et al.
patent: 5631322 (1997-05-01), Veronese et al.
patent: 5643464 (1997-07-01), Rhee et al.
patent: 5644049 (1997-07-01), Giusti et al.
patent: 5656035 (1997-08-01), Avoy
patent: 5672622 (1997-09-01), Hedgepeth et al.
patent: 5702361 (1997-12-01), Evans et al.
patent: 5741223 (1998-04-01), Janzen et al.
patent: 5744545 (1998-04-01), Rhee et al.
patent: 5749968 (1998-05-01), Melanson et al.
patent: 5752974 (1998-05-01), Rhee et al.
patent: 5762620 (1998-06-01), Cartmell et al.
patent: 5773025 (1998-06-01), Baichwal
patent: 5786421 (1998-07-01), Rhee et al.
patent: 5800541 (1998-09-01), Rhee et al.
patent: 5807581 (1998-09-01), Rosenblatt et al.
patent: 5810885 (1998-09-01), Zinger
patent: 5844023 (1998-12-01), Tomka
patent: 5855618 (1999-01-01), Patnaik et al.
patent: 5874500 (1999-02-01), Rhee et al.
patent: 5932462 (1999-08-01), Harris et al.
patent: 5936035 (1999-08-01), Rhee et al.
patent: 5951583 (1999-09-01), Jensen et al.
patent: 6033654 (2000-03-01), Stedronsky et al.
patent: 6046305 (2000-04-01), Choi
patent: 6051248 (2000-04-01), Sawhney et al.
patent: 6051648 (2000-04-01), Rhee et al.
patent: 6110484 (2000-08-01), Sierra
patent: 6124273 (2000-09-01), Drohan et al.
patent: 6150505 (2000-11-01), Marx et al.
patent: 6156531 (2000-12-01), Pathak et al.
patent: 6162241 (2000-12-01), Coury et al.
patent: 6201065 (2001-03-01), Pathak et al.
patent: 6214966 (2001-04-01), Harris
patent: 6251382 (2001-06-01), Greenwald et al.
patent: 6258351 (2001-07-01), Harris
patent: 6312725 (2001-11-01), Wallace et al.
patent: 6371975 (2002-04-01), Cruise et al.
patent: 6458889 (2002-10-01), Trollsas et al.
patent: 6465001 (2002-10-01), Hubbell et al.
patent: 6503731 (2003-01-01), Marx et al.
patent: 2004/0076602 (2004-04-01), Harris
patent: 0557199 (1993-08-01), None
patent: WO 91/09641 (1991-07-01), None
patent: WO 94/03155 (1994-02-01), None
patent: WO 94/13311 (1994-06-01), None
patent: WO 96/03159 (1996-02-01), None
patent: WO 97/22371 (1997-06-01), None
patent: WO 98/35631 (1998-08-01), None
patent: WO 99/10022 (1999-03-01), None
patent: WO 99/14259 (1999-03-01), None
patent: WO 99/22770 (1999-05-01), None
patent: WO 99/34833 (1999-07-01), None
patent: WO 00/12018 (2000-03-01), None
patent: WO 00/72852 (2000-12-01), None
US 6,214,374, 04/2001, Schmirler et al. (withdrawn)
Achterberg et al., “Hydroactive Dressings and Serum Proteins: An In Vitro Study,” J Wound Care 5:79-82 (1996) (abstract).
Baines et al., “Adsorption and Removal of Protein Bound to Hydrogel Contact Lenses,” Optom Vis Sci 67:807-810 (1990) (abstract).
Bick, “Hemostasis Defects,”Seminars in Thrombosis and Hemostasis11:263-264 (1985).
Bite et al., “Macrosorb Kieselguhr-Agarose Composite Adsorbents. New Tools for Downstream Process Design and Scale Up. Scientific Note,”Appl Biochem Biotechnol18:275-284 (1988) (abstract).
Burczak et al., “Protein Permeation Through Poly(Vinyl Alcohol) Hydrogel Membranes,”Biornateria/s15:231-238 (1994) (abstract).
Burgi, “A Simple Method for the Concentration of Protein for Electrophoresis of Urine and Cerebrospinal Fluid,”Z Kim Chem Kim Biochem5:277 (1967) (abstract).
Garrett et al., “Human Serum Albumin Adsorption on Hydrogel Contact Lenses In Vitro,”Invest Aphtha/mol Vis Sci37:2594-2602 (1996) (abstract).
Gayet et al., “High Water Content BSA-PEG Hydrogel for Controlled Release Device: Evaluation of the Drug Release Properties”, Journal of Controlled Release, 38:177-184 (1996).
Irwin et al., “The Effect of Cyclodextrins on the Stability of Peptides in Nasal Enzymic Systems”Pharmaceutical Research, 11(12):1968-1703(1994).
Keller et al., “Determination of the Protein Concentration in the Cerebrospinal Fluid. Criticism of the Methods,”Med Welt23:1319-1325 (1969) (abstract).
Keogh et al., “Albumin binding surfaces for biomaterials”,Laboratory and Clinical Medicine, 124.4:537-545 (1994).
Kissell et al., “Parenteral depot-systems on the basis of biodegradable polyesters”,J of Controlled Release16:27-42 (1991).
Kissell et al., “ABA-triblock Copolymers from Biodegradable Polyester A-blocks and Hydrophilic Poly(ethylene )xide) B-Blocks as a Candidate for In Situ Forming Hydrogel Delivery Systems for Proteins”, Adv. Drug. Deliv. Rev. vol. 54, pp. 99-184 (2002).
Kluge et al., “Results of Comparisons of Various Methods of Determining Total Cerebrospinal Fluid Protein,”Dtsch Gesundheitsw23:2039-2041(1968) (abstract).
Kolthammer, “The In Vitro Adsorption of Drugs from Horse Serum onto Carbon Coated with an Acrylic Hydrogel,”JPhari'n Pharmaco/27:801-805 (1975) (abstract).
Kulik et al., “In Vitro Platelet Adhesion to Nonionic and Ionic Hydrogels with Different Water Contents,”J Biomed Mater Res30:295-304 (1996) (abstract).
Lazarus et al., “Selective In Vivo Removal of Rheumatoid Factor by an Extracorporeal Treatment Device in Rheumatoid Arthri
Dardi & Associates PLLC
Incept LLC
Mohamed Abdel A
Weber Jon P
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