Process for the preparation of 2-(ethoxymethyl)-tropane...

Details Process for the preparation of 2-(ethoxymethyl)-tropane... Process for the preparation of 2-(ethoxymethyl)-tropane...

2005-01-31

2009-06-09

Andres, Janet L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S125000

Reexamination Certificate

active

07544802

ABSTRACT:
The present invention relates to a process for preparing a 2-(ethoxymethyl)-tropane derivative or a pharmaceutically acceptable salt thereof, by reacting the corresponding 2-(hydroxymethyl)-tropane derivative with ethyl bromide in the presence of a base, and a phase transfer catalyst.

REFERENCES:
patent: 6288079 (2001-09-01), Scheel-Kruger et al.
patent: 2004/0106643 (2004-06-01), Gouliaev et al.
patent: 2005/0020621 (2005-01-01), Scheel-Krueger et al.
patent: WO 97/30997 (1997-08-01), None
patent: WO 02/102801 (2002-12-01), None
patent: WO 03/045388 (2003-06-01), None
Burakova et al Russian Chemical Bull. Internation Edition vol. 51 No. 10 pp. 1829-1840 (2002).
Merz, Angew. Chem. Edit. vol. 12 No 10 pp. 846-847 (1973).

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