Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2004-12-06
2009-06-16
Jiang, Shaojia Anna (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S049000, C544S242000, C544S298000, C544S309000, C544S315000, C536S028100, C536S028400
Reexamination Certificate
active
07547704
ABSTRACT:
2′ and/or 3′ prodrugs of 1′, 2′, 3′ or 4′-branched nucleosides, and their pharmaceutically acceptable salts and derivatives are described. These prodrugs are useful in the prevention and treatment of Flaviviridae infections, including HCV infection, and other related conditions. Compounds and compositions of the prodrugs of the present invention are described. Methods and uses are also provided that include the administration of an effective amount of the prodrugs of the present invention, or their pharmaceutically acceptable salts or derivatives. These drugs may optionally be administered in combination or alteration with further anti-viral agents to prevent or treat Flaviviridae infections and other related conditions.
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Gosselin Gilles
LaColla Paola
Sommadossi Jean-Pierre
Storer Richard
Centre National de la Recherche Scientifique
Idenix Pharmaceuticals Inc.
Jiang Shaojia Anna
Jones Day
McIntosh Traviss
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