Tetrasubstituted pyrimidine compounds as chemical intermediates

Details Tetrasubstituted pyrimidine compounds as chemical intermediates Tetrasubstituted pyrimidine compounds as chemical intermediates

2006-12-20

2009-12-08

Rao, Deepak (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C514S274000

Reexamination Certificate

active

07629462

ABSTRACT:
Novel substituted pyrimido[4,5-d]pyrimidin-2-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.

REFERENCES:
patent: 3843663 (1974-10-01), Williams et al.
patent: 4560691 (1985-12-01), Lesher et al.
patent: 4886807 (1989-12-01), Kitamura et al.
patent: 4897395 (1990-01-01), Duch et al.
patent: 5304560 (1994-04-01), Shimazaki et al.
patent: 5409930 (1995-04-01), Spada et al.
patent: 5426110 (1995-06-01), Gossett et al.
patent: 5466692 (1995-11-01), Ellingboe
patent: 5547954 (1996-08-01), Henrie, II et al.
patent: 5597776 (1997-01-01), Bratz et al.
patent: 5620981 (1997-04-01), Blankley et al.
patent: 5733913 (1998-03-01), Blankley et al.
patent: 5733914 (1998-03-01), Blankley et al.
patent: 5760220 (1998-06-01), Giguere et al.
patent: 5767097 (1998-06-01), Tam
patent: 5817670 (1998-10-01), Takayama et al.
patent: 5945422 (1999-08-01), Doherty et al.
patent: 6083948 (2000-07-01), Wilde
patent: 6200977 (2001-03-01), Cusing et al.
patent: 6277989 (2001-08-01), Chakravarty et al.
patent: 6476031 (2002-11-01), Chakravarty et al.
patent: 6479463 (2002-11-01), Wang et al.
patent: 6492520 (2002-12-01), Chen
patent: 6498163 (2002-12-01), Boschelli et al.
patent: 6528508 (2003-03-01), Salituro et al.
patent: 6528513 (2003-03-01), Cusing et al.
patent: 6593333 (2003-07-01), Cumming
patent: 6800626 (2004-10-01), Salituro et al.
patent: 6809199 (2004-10-01), Doherty et al.
patent: 6838559 (2005-01-01), Vaccaro et al.
patent: 6875769 (2005-04-01), Chen
patent: 2003/0114671 (2003-06-01), Chen
patent: 2004/0009993 (2004-01-01), Angiolini
patent: 2004/0063658 (2004-04-01), Roberts et al.
patent: 2004/0116697 (2004-06-01), Adams et al.
patent: 2004/0142945 (2004-07-01), Barbosa et al.
patent: 2004/0209901 (2004-10-01), Adams et al.
patent: 2004/0224958 (2004-11-01), Booth et al.
patent: 2004/0235847 (2004-11-01), Quan et al.
patent: 2004/0236084 (2004-11-01), Biwersi et al.
patent: 2004/0242604 (2004-12-01), Bhattacharya et al.
patent: 2005/0187217 (2005-08-01), Wilson et al.
patent: 2005/0203109 (2005-09-01), Adams et al.
patent: 2005/0272728 (2005-12-01), Altenbach et al.
patent: 2006/0217401 (2006-09-01), Boehm et al.
patent: 2006/0235029 (2006-10-01), Boehm et al.
patent: 2006/0258687 (2006-11-01), Boehm et al.
patent: 0 278 686 (1988-02-01), None
patent: 0 530 994 (1993-03-01), None
patent: 2 123 830 (1984-02-01), None
patent: 1-261306 (1989-10-01), None
patent: 20000038350 (2000-02-01), None
patent: 2003/127542 (2003-05-01), None
patent: 2004-203751 (2004-07-01), None
patent: WO 92/12154 (1992-07-01), None
patent: WO 94/19350 (1994-09-01), None
patent: WO 95/15952 (1995-06-01), None
patent: WO 95/19774 (1995-07-01), None
patent: WO 95/33750 (1995-12-01), None
patent: WO 97/38992 (1997-10-01), None
patent: WO 98/05661 (1998-02-01), None
patent: WO 98/08846 (1998-03-01), None
patent: WO 98/27098 (1998-06-01), None
patent: WO 98/33798 (1998-08-01), None
patent: 99/32121 (1999-07-01), None
patent: WO 99/41253 (1999-08-01), None
patent: WO 99/61444 (1999-12-01), None
patent: WO 99/64400 (1999-12-01), None
patent: WO 00/23444 (2000-04-01), None
patent: WO 00/43374 (2000-07-01), None
patent: WO 01/19828 (2001-03-01), None
patent: WO 01/42243 (2001-06-01), None
patent: WO 01/55147 (2001-08-01), None
patent: WO 01/70741 (2001-09-01), None
patent: WO 02/058695 (2002-08-01), None
patent: WO 02/059083 (2002-08-01), None
patent: WO02/060869 (2002-08-01), None
patent: WO 02/102315 (2002-12-01), None
patent: WO 2005/014558 (2005-02-01), None
El-Reedy et al., CAPLUS Abstract 112:35791, 1990.
Ram Vishnu J., CAPLUS Abstract 112:77090, 1990.
Ram Vishnu J., CAPLUS Abstract 113:78321, 1990.
Ram Vishnu Ji, CAPLUS Abstract 113;97564, 1990.
Ram Vishnu J., CAPLUS Abstract 114:42726, 1991.
Ram et al., CAPLUS Abstract 115:256109, 1991.
Manhi et al., CAPLUS Abstract 121:83254, 1994.
Upadhyay et al., CAPLUS Abstract 131:18977, 1999.
El-Assiery et al., CAPLUS Abstract 132:151761, 1999.
Agarwal et al., Suitably functionalised pyrimidines as potential antimycotic agents, Bioorganic & Medicinal Chemistry Letters, 10(8), 703-706, Apr. 2000.
U.S. Appl. No. 11/613,517, filed Dec. 20, 2006, Adams, et al.
U.S. Appl. No. 11/871,039, filed Oct. 11, 2007, Adams, et al.
U.S. Appl. No. 11/839,830, filed Aug. 16, 2007, Adams, et al.
U.S. Appl. No. 11/839,833, filed Aug. 16, 2007, Adams, et al.
U.S. Appl. No. 11/839,834, filed Aug. 16, 2007, Adams, et al.
U.S. Appl. No. 11/908,340, filed Sep. 11, 2007, Boehm, et al.
U.S. Appl. No. 11/908,435, filed Sep. 12, 2007, Callahan, et al.
U.S. Appl. No. 11/908,440, filed Sep. 12, 2007, Callahan, et al.
U.S. Appl. No. 11/908,839, filed Sep. 17, 2007, Callahan, et al.
Adams et al., Progress in Medicinal Chemistry, vol. 38, pp. 2-61 (2001).
Armarcgo, W., Chem. Soc., Quinazolines, Part IV (JCS OA9) p. 561 (1962).
Boehm et al., J. Med. Chem. vol. 39, pp. 3929-3937 (1996).
Votta et al., Bone, vol. 15 (5) pp. 533-538 (1994).
Bradlerova et al., Chem. Zvesti, vol. 29 (6), pp. 795-802 (1975).
de Silva et al., J. Chem. Soc., vol. 4, pp. 685-690 (1995).
Engel & Steglich, Liebigs Ann. Chem., p. 1916 (1978).
Ferles et al., Collect. Czech. Chem. Commun., 5 (46), pp. 1167-1172 (1981).
Fischer et al., Rec. Trav. Chim. Pays. Bas., vol. 84, p. 439 (1965).
Fulmer et al., J. Heterocycl. Chem., vol. 17 (4), pp. 799-800 (1980).
Gilbert, E., Synthesis, pp. 30-32 (1972).
Han et al., Science, vol. 265, pp. 808-811 (1994).
Hunter et al., Academic Press, San Diego, vol. 200, p. 3 (1991).
Irwin et al., Archives of Internal Medicine, vol. 157 (17), pp. 1981-1987 (1997).
Ishibashi et al., Chem. Pharm. Bull., vol. 37(8), pp. 2214-2216 (1989).
Johnson et al., PG.A., J.Chem.Soc., Perkin Trans., vol. 1, pp. 895-905 (1996).
Jurkowska-Kowalczyk, R., Chem., vol. 51 (6), pp. 1191-1199 (1977).
Katritzky et al., Synthesis, pp. 45-47 (Jan. 1993).
Kawasaki et al., J. Bio. Chem., vol. 272(30), pp. 18518-18521 (1997).
Mikailu et al., Zh. Obshch. Khim., vol. 56 (7), pp. 1513-1517 (1986).
Morton et al., Tetrahedron Letters, p. 4123 (1982).
Protecting Groups in Organic Synthesis, 2ndEdition, Greene TW and Wuts PSM, Wiley-Interscience, New York, pp. 10-174 (Hydroxyl and Phenolic) and pp. 309-403 (NH protection) (1991).
Santilli et al., J. Heterocycl Chem., vol. 8, pp. 445-453 (1971).
Snieckus, V., Tetrahedron Letters, vol. 29, p. 2135 (1988).
Stille et al., J. Amer. Chem. Soc., vol. 109, p. 5478 (1978).
Strzybny et al., J. Org. Chem., vol. 28, p. 3381 (1963).
Terashimia et al., M., Chem. Pharm. Bull., vol. 11, p. 4755 (1985).
Thompson et al., J. Org. Chem., vol. 49, p. 5237 (1984).
Uno et al., Bull. Chem. Soc. Japan., vol. 69, pp. 1763-1767 (1996).
Vartanyan et al., vol. 40, (9), pp. 552-560 (1987).
Borrel, et al., Coll. Czech. Chem. Commun., 1996, 61(6) pp. 901-909.
Hurlbert, et al., J. Med. Chem., 1968, vol. 11, pp. 703-707.
Baker et al., J. Heterocyclic Chem., 1964, vol. 1, pp. 263-270.
Anderson et al., J. Org. Chem., 1977, vol. 42, p. 993.
Schoffstall et al., J. Org. Chem., 1971, 36(16), pp. 2385-2387.
Victory et al., Heterocycles, 1985, 23(5), pp. 1135-1141.
Gallagher et al., Bioorganic and Med Chem, vol. 5(1), pp. 49-64 (1997).
Garigipati, R., Tetrahedron Letters, vol. 31,p. 190 (1989).
Kumada et al., Tetrahedron Letters, vol. 22, p. 5319 (1981).
Lamartina et al., Boll. Chim. Farm., vol. 129 (12), pp. 314-316 (1990).
Victory et al., Heterocycles, 1985, 23(8), pp. 1947-1950.
Victory et al., AFINIDAD, Mar. 1989, vol. 46, pp. 107-113 (Spanish).
Victory et al., J. Heterocycl. Chem, 1988, vol. 25, pp. 245-247.
Klotzer et al., Monatsh Chem., 1965, vol. 96, p. 1567.
Nishikawa et al., Chemical Pharm. Bull., 1976, vol. 24(9), pp. 2057-2077.
Carboni et al.,Gazzetta Chimica Italiana, vol. 97(8) pp. 1262-1273 (1967).
Carboni et al.,Gazzetta Chimica Italiana, vol. 98(10) pp. 1174-1188 (1968).
Ferrarini et al.,Journal of Heterocyclic Chemistry, vol. 21(2) pp. 417-419 (1984).
Ferrarini et al.,Journal of Heterocyclic Chemistry, vol. 34(5) pp. 1501-1510 (1997).
Rewcastle et al., Journal of Medicinal Chemistry, 1996 39(6), pp. 1823-1835.
Zavyalov, et al., Khim Farm Zh, vol. 26(3), p. 88 (1992) (With Translation).

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