AXMI-028 and AXMI-029, a family of novel delta-endotoxin...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C435S069100, C514S04400A

Reexamination Certificate

active

07622572

ABSTRACT:
Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a delta-endotoxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated delta-endotoxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, 4, 15, 17, or 19, or the nucleotide sequence set forth in SEQ ID NO:1, 3, 14, 16, or 18, as well as variants and fragments thereof.

REFERENCES:
patent: 0 382 990 (1990-08-01), None
patent: WO 93/08693 (1993-05-01), None
patent: WO 9308693 (1993-05-01), None
patent: WO 2004/074462 (2004-09-01), None
Result 1, Geneseq database search, alignment of SEQ ID No. 1 with SEQ ID No. 3 of Mycogen Corp., WO 93/08693 A1, searched on Jun. 10, 2007.
Pre-OG notice, Examination of patent applications containing nucleotide sequences, (http://www.uspto.gov/web/offices/pac/dapp/opla/ preognotice/sequence02212007.pdf), printed on Jun. 13, 2007.
Guo et al., “Protein tolerance to random amino acid change,” Proc Natl Acad Sci USA 101(25):9205-9210, 2004.
Guo et al., “Protein Tolerance to Random Amino Acid Change”, PNAS 101(25):9205-9210, 2004.
NCBI Database Report for Accession No. Q03749, Mar. 21, 2006.
NCBI Database Report for Accession No. Q45707, Mar. 21, 2006.
NCBI Database Report for Accession No. Q45708, Mar. 21, 2006.

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