Induced nuclear reactions: processes – systems – and elements – Nuclear transmutation – By charged particle bombardment
Reexamination Certificate
2003-10-20
2009-08-18
Langel, Wayne (Department: 1793)
Induced nuclear reactions: processes, systems, and elements
Nuclear transmutation
By charged particle bombardment
C376S196000, C376S198000, C378S198000, C422S903000
Reexamination Certificate
active
07577228
ABSTRACT:
The invention relates to a manufacturing facility comprising a building structure which encloses working space of the manufacturing facility, the building structure being designed to house a cyclotron and to be transportable by truck or rail to a destination site, wherein the manufacturing facility, except for lacking a cyclotron during transport, is substantially equipped during transport to produce and package a radiopharmaceutical. The invention also relates to a method of providing a manufacturing facility for producing a radioactive material, the method comprising the steps of designing the manufacturing facility to receive a cyclotron; equipping the manufacturing facility with a synthesis unit which is designed to receive a first radioactive material from the cyclotron and to produce a second radioactive material; transporting the manufacturing facility to a site; transporting the cyclotron to the site; and enclosing the cyclotron inside the manufacturing facility. The manufacturing facility may be relocated to another site without substantial effort.
REFERENCES:
patent: 3411002 (1968-11-01), Armel
patent: 4428908 (1984-01-01), Ashley et al.
patent: 4943781 (1990-07-01), Wilson et al.
patent: 5037602 (1991-08-01), Dabiri et al.
patent: 5210421 (1993-05-01), Gullberg et al.
patent: 5871013 (1999-02-01), Wainer et al.
patent: 5927351 (1999-07-01), Zhu et al.
patent: 5932878 (1999-08-01), Heukensfeldt et al.
patent: 6162417 (2000-12-01), Goodman et al.
patent: 6392246 (2002-05-01), Wiberg et al.
patent: 6437344 (2002-08-01), Strawson
patent: 6445146 (2002-09-01), Bergstrom et al.
patent: 6481887 (2002-11-01), Mirabella
K. Hamacher, H.H. Coenen and G. Stocklin, J. Nucl. Med., 1986, 27, 235.
K. Hamacher, H.H. Coenen, and G. Stocklin, “Efficient Stereospecific Synthesis of No-Carrier-Added 2-[18F]-Fluoro-2-Deoxy-D-Glucose Using Aminopolyether Supported Nucleophilic Substitution,” 27 J. Nucl. Med., 235-238 (1986).
C. Lemaire et al., “Synthesis of [18F]FDG with Alkaline Hydrolysis on a Low Polarity Solid Phase Support,” 40 J. Labelled Compd. Radiopharm. 256 (1997).
C. Mosdzianowski et al., “Routine and Multi-Curie Level Productions of [18F]FDG using an Alkaline Hydrolysis on Solid Support,” 42 J. Labelled Cpd. Radiopharm. 515 (1999).
Patent Cooperation Treaty (PCT) International Search Report, PCT/US/03/33721, Apr. 23, 2004.
General Electric Company
Hunton & Williams LLP
Langel Wayne
Martinez Brittany M
LandOfFree
Transportable manufacturing facility for radioactive materials does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Transportable manufacturing facility for radioactive materials, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transportable manufacturing facility for radioactive materials will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4083404