Process for producing 5-hydroxy-4-thiomethylpyrazole compound

Details Process for producing 5-hydroxy-4-thiomethylpyrazole compound Process for producing 5-hydroxy-4-thiomethylpyrazole compound

2005-03-31

2009-02-10

Shiao, Rei-Tsang (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S407000

Reexamination Certificate

active

07488831

ABSTRACT:
A pyrazole compound represented by general formula (1) is reacted with a sulfur compound represented by general formula (2) in the presence of a base and formaldehyde, to thereby produce a 5-hydroxy-4-thiomethylpyrazole compound represented by general formula (3). The 5-hydroxy-4-thiomethylpyrazole compound may easily be produced in a good yield, by using such a process. Further, this process may easily provide the 5-hydroxy-4-thiomethylpyrazole compound under a mild condition in a single step, without using a special apparatus, an expensive catalyst, or a transition metal, etc. In addition, this process may be conducted substantially without producing a harmful waste which can be derived from a catalyst, etc., and therefore this process is friendly to the environment and industrially valuable.

REFERENCES:
patent: 2001/064651 (2001-09-01), None
patent: WO-01/64651 (2001-09-01), None
patent: 2002/062770 (2002-08-01), None
patent: 2003/000686 (2003-01-01), None
patent: 2004/013106 (2004-02-01), None
patent: 2004/014138 (2004-02-01), None

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