Use of the gene NcSAG4 for the diagnosis and prevention of...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C435S975000

Reexamination Certificate

active

07579438

ABSTRACT:
The invention relates to gene NcSAG4, the RNA messenger of said gene, the oligonucleotides designed based on the nucleotide sequence thereof or any of the fragments of same, and to protein NcSAG4 encoded thereby, or any of the recombinant forms of same, expression vectors, and host cells containing same, for the purpose of diagnosis and vaccination for the prevention of neosporosis. The invention also relates to the use thereof as a specific marker of theN. caninumbradyzoite stage, for the analysis of the pathogenesis or the effectiveness of vaccines against the establishment of a chronic infection in the intermediate host.

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Wouda, W. e

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