Modulation of survivin expression

Details Modulation of survivin expression Modulation of survivin expression

2004-06-03

2009-06-02

McGarry, Sean R (Department: 1635)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C435S006120, C435S375000, C435S377000, C536S023100, C536S024100, C536S024500

Reexamination Certificate

active

07541344

ABSTRACT:
Compounds and compositions are provided for modulating the expression of survivin. The compounds, exemplified by those acting through an RNAi antisense mechanism of action, include double-stranded and single-stranded constructs, as well as siRNAs, canonical siRNAs, blunt-ended siRNAs and single-stranded antisense RNA compounds. Methods of using these compounds for modulation of survivin expression and for treatment of diseases associated with expression of survivin are provided.

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