Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus containing
Reexamination Certificate
2007-02-16
2009-02-17
Sullivan, Daniel M (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Phosphorus containing
C568S008000, C568S009000
Reexamination Certificate
active
07491851
ABSTRACT:
This invention provides a method for generating secondary phosphines from secondary phosphine oxides in the presence of a reducing agent, such as diisobutylaluminum hydride (DIBAL-H), triisobutyldialuminoxane, triisobutylaluminum, tetraisobutyldialuminoxane, or another reducing agent comprising: (i) an R1R2AlH moiety, wherein R1and R2are each an alkyl species or oxygen, and wherein at least one of R1or R2comprises at least 2 carbon atoms, or (ii) an R1R2R3Al moiety, wherein R1, R2, and R3are not hydrogen, and wherein at least one of R1, R2, and R3is an alkyl species comprising a β-hydrogen, not including triethylaluminum. Preferred reducing agents for the present invention include: diisobutylaluminum hydride, triisobutyldialiuminoxane, triisobutylaluminum, tetraisobutyldialuminoxane, and combinations thereof.
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Busacca Carl Alan
Lorenz Jon C.
Boehringer Ingelheim Pharmaceuticals Inc.
Devlin Mary-Ellen M.
Kershner David L.
Morris Michael P.
Nwaonicha Chukwuma O
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