Aminoalkylthiodibenzoxepins and pharmaceutical use

Details Aminoalkylthiodibenzoxepins and pharmaceutical use Aminoalkylthiodibenzoxepins and pharmaceutical use

1985-05-28

1989-06-06

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142328, 514253, 514320, 514422, 544147, 544375, 546196, 548525, 549354, A61K 31335, C07D31314

Patent

active

048372277

ABSTRACT:
Novel aminoalkylthiodibenzoxepins, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as analgesic, antidepressant and anticonvulsant agents. A process for selectively reducing olefins by alkaline earth metals in loweralkanols is also disclosed.

REFERENCES:
patent: 3524855 (1970-08-01), Schindler et al.
patent: 3704245 (1972-11-01), Umio et al.
patent: 3991103 (1976-11-01), Barton et al.
patent: 4668695 (1987-05-01), Ong et al.
Protiva, Il Farmaco, vol. XXI (1966) pp. 76-104.
Protiva et al, Il Farmaco, vol. XX (1965) pp. 721-725.
V. Bartl et al, Collection of Czechoslovak Chemical Communications, vol. 43 (1978) pp. 2427-2443.
Dostert et al, Eur. J. Med. Chem. Chimica Therapeutica, May-Jun. 1974, vol. 9, No. 3, pp. 259-262.
V. Seidlova, et al., Coll. Czech. Chem. Comm., 34, 2258-2277 (1969).
S. Umio, et al., Chem. Abs. 72, 55287r (1970).
H. Allgeier & E. Schmidt, Chem. Abs., 85, 32888s (1976).
I. Ueda, et al., Chem. Pharm. Bull., 26, 30583070 (1978).
S. Uchida, et al., Arzneim-Forsh./Drug Res., 29 (II) No. 10 1588-1600 (1979).
L. Chekhovskaya, et al., Chem. Abs., 71, 49433y (1969).
J. A. Profitt and H. Ong, J. Org. Chem., 44(22), pp. 3972-3974 (1979).
H. H. Ong, et al., J. Med. Chem., 23, 494-501 (1980).
V. Hahn, Chem. Abs., 50, 292f (1956).
R. Hansel, et al., Chem. Abs., 50, 4894 (1956).
P. Camps, et al., Tetrahedron, 32, 2583-2587 (1976).
G. Schroeter, et al., Chem. Ber., 62, 645-658 (1929).
L. M. Chekhovskaya, et al., Chem. Abs., 75, 151085f (1971).
J. Wiemann, Bull. Soc. Chem. France, C25-27 (1953).
J. A. Profitt, et al., J. Org. Chem., 40(1), 127-128 (1975).
L. Zechmeister et al, Ann., 468, 117-132 (1928).
M. L. Raggio and D. S. Watt, J. Org. Chem., 41(10), 1873-1875 (1976).
R. Brettle and SA-AD M. Shibib, Tetrahedron Letters 21, 2915-2916 (1980).
G. A. Olah, et al., Angew. Chem. Int. Ed. Engl., 20, 92-93 (1981).

Affiliated with

Also associated with

Rating

Aminoalkylthiodibenzoxepins and pharmaceutical use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aminoalkylthiodibenzoxepins and pharmaceutical use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aminoalkylthiodibenzoxepins and pharmaceutical use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-40733