Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Patent
1981-03-16
1982-12-21
Mars, Howard T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
568683, C07C 4101
Patent
active
043650970
ABSTRACT:
Processes for the preparation of certain halogenated aliphatic ethers are described, and in particular the preparation of 1,1,2-trifluoro-2-chloroethyl methyl ether, i.e., CH.sub.3 OCF.sub.2 CHFCl. This particular ether has many uses, and is a valuable material for use in the production of the inhalant anesthetic enflurane, 1,1,2-trifluoro-2-chloroethyl difluoromethyl ether, i.e., CF.sub.2 HOCF.sub.2 CHFCl, made and sold under the trademark ETHRANE by Airco, Inc., Montvale, New Jersey 07645.
REFERENCES:
patent: 2332467 (1943-10-01), Linn et al.
patent: 3931238 (1976-01-01), Starks
Freedman et al., Tetrahedron Letters, No. 38, pp. 3251-3254, 1975.
Herreott et al., Tetrahedron Letters, No. 44, pp. 4521-4524, 1972.
Corley et al., J. Am. Chem. Soc., 78, pp. 3489-3492, 1956.
Scipioni et al., Translation Ann. Chim. Rome, 1967, 57(7), 817-824.
Hansen Kirsten
Terrell Ross C.
Airco, Inc.
Cassett Larry R.
Mars Howard T.
Rathbun Roger M.
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