Modulating apoptosis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C530S350000

Reexamination Certificate

active

07638485

ABSTRACT:
The use and screening of modulators of apoptosis is disclosed. The modulators may be, for example, modulator of NF-κB activity. The modulators may be used, for example, in the treatment of NF-κB-mediated diseases, conditions, and injuries.

REFERENCES:
patent: 5399494 (1995-03-01), Kaper et al.
patent: 6130082 (2000-10-01), Majarian et al.
Bachmann, M.F., Wolint, P., Schwarz, K., and Oxenius, A. Recall proliferation potential of memory CD8+ T cells and antiviral protection. 2005 Journal of Immunology, vol. 175, pp. 4677-4685.
Das, U.N. A radical approach to cancer. 2002 Medical Science Monitor, vol. 8 No. 4, pp. RA79-RA92.
Efferson,.C.L., Kawano, K., Tsuda, N., Palese, P., Garcia-Sastre, A., and Ioannides, C.G. Stimulation of human T cells by an influenza A vector expressing a CTL epitope from the HER-2
eu protooncogene results in higher numbers of antigen-specific TCRhi cells than stimulation with peptide. 2005 Anticancer Research vol. 25, pp. 715-724.
Wheeler, C.M. Preventative vaccines for cervical cancer. 1997, Salud Publica de Mexico, vol. 39 No. 4.
Androstenediol and Androstenedione. Wikipedia. http://en.wikipedia.org/wiki.
Definition of prophylaxis, Stedman's Medical Dictionary, 27thedition online, 2000.
Definition of prophylaxis, Merriam-Webster Medical Dictionary, online edition, 2005.
Cholera, Wikipedia, 2008.
Carnes et al., Radiation Research 160(2):159-167 (2003) (abstract only).
Burdelya et al., “An Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models,” Science Apr. 11, 2008, (320) pp. 226-230.
Hall, “Physics and Chemistry of Radiation Absorption,” Radiobiology for the Radiobiologist, pp. 5-15, 5th ed., Lippincott Williams and Wilkins, Phila., PA, 2000.
Andreassen CN, et al., Chemical radioprotection: a critical review of amifostine as a cytoprotector in radiotherapy, Semin Radiat Oncol., 2003;13(1):62-72.
Seed T, et al., New strategies for the prevention of radiation injury: possible implications for countering radiation hazards of long-term space travel, J Radiat Res, 2002;43 Suppl:S239-44.
Waddick KG, et al., In vitro and in vivo antileukemic activity of B43-pokeweed antiviral protein against radiation-resistant human B-cell precursor leukemia cells, Blood., 1995;86(11):4228-33.
Satyamitra M, et al., In vivo postirradiation protection by a vitamin E analog, alpha-TMG, Radiat Res. 2003;160 (6):655-61.
Eaves-Pyles TD, et al.,Salmonellaflagellin-dependent proinflammatory responses are localized to the conserved amino and carboxyl regions of the protein, J Immunol. Dec. 15, 2001;167(12):7009-16.
Sredni B, et al., The immunomodulator AS101 administered orally as a chemoprotective and radioprotective agent. Int J Immunopharrnacol, 1992;14(4):613-9.
Symon Z, et al., Selective radioprotection of hepatocytes by systemic and portal vein infusions of amifostine in a rat liver tumor model, Int J Radiat Oncol Biol Phys., 2001;50(2):473-8.
Mutlu-Turkoglu U, et al., The effect of selenium and/or vitamin E treatments on radiation-induced intestinal injury in rats, Life Sci., 2000;66(20):1905-13.
Patchen ML, Amifostine plus granulocyte colony-stimulating factor therapy enhances recovery from supralethal radiation exposures: preclinical experience in animals models, Eur J Cancer., 1995;31A Suppl 1:S17-21.
Streeter PR, et al., Activation of the G-CSF and Flt-3 receptors protects hematopoietic stem cells from lethal irradiation, Exp Hematol., 2003;31(11):1119-25.
Wong GH, Protective roles of cytokines against radiation: induction of mitochondrial MnSOD, Biochim Biophys Acta., 1995:1271(1):205-9.
Whitnall MH, et al., In vivo radioprotection by 5-androstenediol: stimulation of the innate immune system, Radiat Res., 2001;156(3):283-93.

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