Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-10-04
2009-10-20
Coleman, Brenda L (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S259300, C514S252160, C514S228500, C514S234200, C514S255050, C544S218000, C544S230000, C544S117000, C544S058200, C540S575000
Reexamination Certificate
active
07605155
ABSTRACT:
In its many embodiments, the present invention provides a class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases (CDKs), methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions. All illustrative compound is shown below:
REFERENCES:
Wolff, Manfred E. “Burger's Medicinal Chemistry, 5ed, Part I”, John Wiley & Sons, 1995, pp. 975-977.
Banker, G.S. et al, “Modern Pharmaceutics, 3ed.”, Marcel Dekker, New York, 1996, pp. 451 and 596.
Vippagunta et. al., Advanced Drug Delivery, 2001,, 48, 3-26.
Dwyer Michael P.
Guzi Timothy J.
Keertikar Kartik M.
Labroli Marc
Paruch Kamil
Coleman Brenda L
Kalyanaraman Palaiyur S.
Moore Susanna
Schering Corporation
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