Bis-esters of alkanediols as antibacterial agents

Details Bis-esters of alkanediols as antibacterial agents Bis-esters of alkanediols as antibacterial agents

1981-02-20

1982-12-21

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

2602452R, 2602391, 424270, 424114, C07D49944, A61K 3143

Patent

active

043649572

ABSTRACT:
6-Acylaminopenicillanoyloxymethyl esters and 1-(6-acylaminopenicillanoyloxy)ethyl esters of 2-beta-acetoxymethyl-2-alpha-methyl-(5R)penam-3-alpha-carboxylic acid 1,1-dioxide are useful as antibacterial agents. The 6-aminopenicillanoyloxymethyl ester, the 1-(6-aminopenicillanoyloxy)ethyl ester and certain other mono-substituted methyl and ethyl esters of 2-beta-acetoxymethyl-2-alpha-methyl-(5R)penam-3-alpha-carboxylic acid 1,1-dioxide are useful intermediates to the aforesaid antibacterial agents.

REFERENCES:
patent: 4234579 (1980-11-01), Barth
patent: 4244951 (1981-01-01), Bigham
patent: 4256733 (1981-04-01), Barth

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