High-molecular weight derivatives of camptothecins

Details High-molecular weight derivatives of camptothecins High-molecular weight derivatives of camptothecins

2003-10-29

2009-02-24

Aulakh, Charanjit S (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S283000, C546S014000

Reexamination Certificate

active

07495099

ABSTRACT:
It is intended to provide water-soluble derivative of camptothecins which are excellent in therapeutic effect and suitable for chemotherapy for cancer. Namely, a water-soluble high-molecular weight derivative of camptothencins being excellent in sustained-release which is obtained by ester-bonding a carboxylic acid group of a polyethylene glycol-polycarboxylic acid polymer to a phenolic hydroxyl group of phenolic camptothencins.

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