Methods for the synthesis of unsymmetrical cycloalkyl...

Details Methods for the synthesis of unsymmetrical cycloalkyl... Methods for the synthesis of unsymmetrical cycloalkyl...

2006-02-27

2009-10-06

Berch, Mark L (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen bonded directly to ring carbon of the purine ring...

C544S268000, C544S270000, C544S273000, C544S310000, C544S311000, C544S312000

Reexamination Certificate

active

07598379

ABSTRACT:
The present invention provides processes for making pyridyl-linked-xanthines of formula VII, from 5,6-diamino-1H-pyrimidine-2,4-diones of formula II and acylating agents of formula VI.The xanthines are expected to be are selective antagonists of A2Badenosine receptors (ARs).

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Science 310, p. 409 (Oct. 21, 2005).
Jacobson et al, Journal of Medicinal Chemistry (1993) 36, 1333.

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