Thiophene-2-carboxamide derivatives, preparation and...

Details Thiophene-2-carboxamide derivatives, preparation and... Thiophene-2-carboxamide derivatives, preparation and...

2006-04-07

2008-12-09

Shiao, Rei-Tsang (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S414000, C514S444000, C514S448000, C546S207000, C548S465000, C549S059000, C549S072000

Reexamination Certificate

active

07462631

ABSTRACT:
The invention discloses and claims a compound of formula (I):Wherein R1, R2, R3, R4, R5, R6, R7, R8and R11are as defined herein. Further embodiments of the invention include a method of preparation of a compound of formula (I), its pharmaceutical composition and a method of treatment of a disease using a compound of formula (I).

REFERENCES:
patent: 0728755 (1996-08-01), None
patent: WO 91/19708 (1991-12-01), None
patent: WO 91/19708 (1991-12-01), None
patent: WO 95/00501 (1995-01-01), None
patent: WO 03/037886 (2003-05-01), None
Shvedov, V.I., et. al., Synthesis and Biological Activity of 5-Aryithiphene-2-Carboxylic Acid Derivatives, Khimicko-Farmatsevticheskii Zhurnal, vol. 12, No. 11, (1978) pp. 53-56.
Tsuji, K., et. al., Studies on Anti-Inflammatory Agents. VI. 1) Synthesis and Pharmacological Properties of 2,3-Diarylthiophenes, Chem Pharm. Bull., vol. 46(2), pp. 279-286 (1998).

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