Placental stem cells

Details Placental stem cells Placental stem cells

2004-06-22

2008-12-23

Li, Q. Janice (Department: 1633)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C424S093100

Reexamination Certificate

active

07468276

ABSTRACT:
The present invention provides a method of extracting and recovering embryonic-like stem cells, including, but not limited to pluripotent or multipotent stem cells, from an exsanguinated human placenta. A placenta is treated to remove residual umbilical cord blood by perfusing an exsanguinated placenta, preferably with an anticoagulant solution, to flush out residual cells. The residual cells and perfusion liquid from the exsanguinated placenta are collected, and the embryonic-like stem cells are separated from the residual cells and perfusion liquid. The invention also provides a method of utilizing the isolated and perfused placenta as a bioreactor in which to propagate endogenous cells, including, but not limited to, embryonic-like stem cells. The invention also provides methods for propagation of exogenous cells in a placental bioreactor and collecting the propagated exogenous cells and bioactive molecules therefrom.

REFERENCES:
patent: 3862002 (1975-01-01), Sanders
patent: 4829000 (1989-05-01), Kleinman
patent: 5004681 (1991-04-01), Boyse et al.
patent: 5192553 (1993-03-01), Boyse et al.
patent: 5197985 (1993-03-01), Caplan et al.
patent: 5226914 (1993-07-01), Caplan et al.
patent: 5272071 (1993-12-01), Chappel
patent: 5372581 (1994-12-01), Anderson
patent: 5415665 (1995-05-01), Hessel et al.
patent: 5437994 (1995-08-01), Emerson et al.
patent: 5460964 (1995-10-01), McGlave et al.
patent: 5464764 (1995-11-01), Capecchi et al.
patent: 5486359 (1996-01-01), Caplan et al.
patent: 5487992 (1996-01-01), Capecchi et al.
patent: 5516532 (1996-05-01), Atala et al.
patent: 5591625 (1997-01-01), Gerson et al.
patent: 5605822 (1997-02-01), Emerson et al.
patent: 5627059 (1997-05-01), Capecchi et al.
patent: 5635386 (1997-06-01), Palsson et al.
patent: 5635387 (1997-06-01), Fei et al.
patent: 5643741 (1997-07-01), Tsukamoto et al.
patent: 5646043 (1997-07-01), Emerson et al.
patent: 5654186 (1997-08-01), Cerami et al.
patent: 5654381 (1997-08-01), Hrkach et al.
patent: 5665557 (1997-09-01), Murray et al.
patent: 5668104 (1997-09-01), Nakahata et al.
patent: 5670147 (1997-09-01), Emerson et al.
patent: 5670351 (1997-09-01), Emerson et al.
patent: 5672346 (1997-09-01), Srour et al.
patent: 5709854 (1998-01-01), Griffith-Cima et al.
patent: 5716616 (1998-02-01), Prockop et al.
patent: 5716794 (1998-02-01), Tjota et al.
patent: 5716827 (1998-02-01), Tsukamoto
patent: 5733541 (1998-03-01), Taichman et al.
patent: 5733542 (1998-03-01), Haynesworth et al.
patent: 5736396 (1998-04-01), Bruder et al.
patent: 5744361 (1998-04-01), Hoffman et al.
patent: 5750397 (1998-05-01), Tsukamoto et al.
patent: 5763197 (1998-06-01), Tsukamoto et al.
patent: 5763266 (1998-06-01), Palsson et al.
patent: 5807686 (1998-09-01), Wagner et al.
patent: 5811094 (1998-09-01), Caplan et al.
patent: 5827735 (1998-10-01), Young et al.
patent: 5827740 (1998-10-01), Pittenger
patent: 5827742 (1998-10-01), Scadden
patent: 5837539 (1998-11-01), Caplan et al.
patent: 5849553 (1998-12-01), Anderson et al.
patent: 5851984 (1998-12-01), Matthews et al.
patent: 5855619 (1999-01-01), Caplan et al.
patent: 5858782 (1999-01-01), Long et al.
patent: 5861315 (1999-01-01), Nakahata
patent: 5866414 (1999-02-01), Badylak et al.
patent: 5874301 (1999-02-01), Keller et al.
patent: 5877299 (1999-03-01), Thomas et al.
patent: 5879318 (1999-03-01), Van Der Heiden et al.
patent: 5879940 (1999-03-01), Torok-Storb et al.
patent: 5905041 (1999-05-01), Beug et al.
patent: 5906934 (1999-05-01), Grande et al.
patent: 5908782 (1999-06-01), Marshak et al.
patent: 5908784 (1999-06-01), Johnstone et al.
patent: 5914108 (1999-06-01), Tsukamoto et al.
patent: 5914268 (1999-06-01), Keller et al.
patent: 5916202 (1999-06-01), Haswell
patent: 5919176 (1999-07-01), Kuypers et al.
patent: 5919702 (1999-07-01), Purchio et al.
patent: 5922597 (1999-07-01), Verfaillie et al.
patent: 5925567 (1999-07-01), Kraus et al.
patent: 5928214 (1999-07-01), Rubinstein et al.
patent: 5928947 (1999-07-01), Anderson et al.
patent: 5942225 (1999-08-01), Bruder et al.
patent: 5942496 (1999-08-01), Bonadio et al.
patent: 5958767 (1999-09-01), Snyder et al.
patent: 5962325 (1999-10-01), Naughton et al.
patent: 5968829 (1999-10-01), Carpenter
patent: 5969105 (1999-10-01), Feng et al.
patent: 5993429 (1999-11-01), Kuypers et al.
patent: 5997860 (1999-12-01), Bauer et al.
patent: 6001654 (1999-12-01), Anderson et al.
patent: 6010696 (2000-01-01), Caplan et al.
patent: 6011000 (2000-01-01), Faller et al.
patent: 6020469 (2000-02-01), Hershenson
patent: 6022540 (2000-02-01), Bruder et al.
patent: 6022743 (2000-02-01), Naughton et al.
patent: 6022848 (2000-02-01), Kozlov et al.
patent: 6030836 (2000-02-01), Thiede
patent: 6057123 (2000-05-01), Craig et al.
patent: 6059968 (2000-05-01), Wolf, Jr.
patent: 6077708 (2000-06-01), Collins et al.
patent: 6087113 (2000-07-01), Caplan et al.
patent: 6093531 (2000-07-01), Bjornson et al.
patent: 6110739 (2000-08-01), Keller et al.
patent: 6127135 (2000-10-01), Hill et al.
patent: 6146888 (2000-11-01), Smith et al.
patent: 6174333 (2001-01-01), Kadiyala et al.
patent: 6179819 (2001-01-01), Haswell
patent: 6184035 (2001-02-01), Csete et al.
patent: 6190368 (2001-02-01), Kuypers et al.
patent: 6214369 (2001-04-01), Grande et al.
patent: 6224860 (2001-05-01), Brown
patent: 6225119 (2001-05-01), Qasba et al.
patent: 6227202 (2001-05-01), Matapurkar
patent: 6231880 (2001-05-01), Perrine
patent: 6239157 (2001-05-01), Mbalaviele et al.
patent: 6248587 (2001-06-01), Rodgers et al.
patent: 6251383 (2001-06-01), Upadhyay et al.
patent: 6255112 (2001-07-01), Thiede et al.
patent: 6261549 (2001-07-01), Fernandez et al.
patent: 6280718 (2001-08-01), Kaufman et al.
patent: 6281012 (2001-08-01), McIntosh et al.
patent: 6300314 (2001-10-01), Wallner et al.
patent: 6306575 (2001-10-01), Thomas et al.
patent: 6312950 (2001-11-01), Ohmura et al.
patent: 6322784 (2001-11-01), Pittenger et al.
patent: 6326019 (2001-12-01), Tseng
patent: 6326198 (2001-12-01), Emerson et al.
patent: 6328765 (2001-12-01), Hardwick et al.
patent: 6328960 (2001-12-01), McIntosh et al.
patent: 6335195 (2002-01-01), Rodgers et al.
patent: 6337387 (2002-01-01), Sakano et al.
patent: 6338942 (2002-01-01), Kraus et al.
patent: 6355239 (2002-03-01), Bruder et al.
patent: 6368636 (2002-04-01), McIntosh et al.
patent: 6379953 (2002-04-01), Bruder et al.
patent: 6387367 (2002-05-01), Davis-Sproul et al.
patent: 6387369 (2002-05-01), Pittenger et al.
patent: 6461645 (2002-10-01), Boyse et al.
patent: 6497875 (2002-12-01), Sorrell et al.
patent: 6541024 (2003-04-01), Kadiyala et al.
patent: 6685936 (2004-02-01), McIntosh et al.
patent: 6709864 (2004-03-01), Pittenger et al.
patent: 6797269 (2004-09-01), Mosca et al.
patent: 6835377 (2004-12-01), Goldberg et al.
patent: 6863900 (2005-03-01), Kadiyala et al.
patent: 6875430 (2005-04-01), McIntosh et al.
patent: 6875607 (2005-04-01), Reubinoff et al.
patent: 7029666 (2006-04-01), Bruder et al.
patent: 7045148 (2006-05-01), Hariri
patent: 7255879 (2007-08-01), Hariri
patent: 7311904 (2007-12-01), Hariri
patent: 7311905 (2007-12-01), Hariri
patent: 2001/0005591 (2001-06-01), Qasba et al.
patent: 2002/0123141 (2002-09-01), Hariri
patent: 2002/0132343 (2002-09-01), Lum
patent: 2003/0044977 (2003-03-01), Sakuragawa et al.
patent: 2003/0235563 (2003-12-01), Strom et al.
patent: 2004/0018617 (2004-01-01), Hwang
patent: 2004/0028660 (2004-02-01), Hariri
patent: 2004/0048372 (2004-03-01), Hariri
patent: 2004/0048796 (2004-03-01), Hariri
patent: 2004/0107453 (2004-06-01), Furchi et al.
patent: 2004/0136967 (2004-07-01), Weiss et al.
patent: 2004/0161419 (2004-08-01), Strom et al.
patent: 2004/0171147 (2004-09-01), Hariri
patent: 2004/0180040 (2004-09-01), Phillips et al.
patent: 2004/0219136 (2004-11-01), Hariri
patent: 2004/0229351 (2004-11-01), Rodriguez et al.
patent: 2005/0019865 (2005-01-01), Kihm et al.
patent: 2005/0032209 (2005-02-01), Messina et al.
patent: 2005/0037491 (2005-02-01), Mistry et al.
patent: 2005/0042595 (2005-02-01), Haas
patent: 2005/0054093 (2005-03-01), Haas
patent: 2005/0054098 (2005-03-01), Mistry et al.
patent: 2005/0058629 (2005

Affiliated with

Also associated with

Rating

Placental stem cells does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Placental stem cells, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Placental stem cells will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4049518