Triple monoamine reuptake inhibitors for the treatment of...

Details Triple monoamine reuptake inhibitors for the treatment of... Triple monoamine reuptake inhibitors for the treatment of...

2003-05-27

2008-12-02

Morris, Patricia L (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

Reexamination Certificate

active

07459464

ABSTRACT:
The present invention relates to the use of triple monoamine reuptake inhibitors for the treatment of chronic pain.

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Yamamoto & Nozaki-Taguchi, Analysis of the Effects of Cyclooxygenase (XOX)-1 and COX-2 in Spinal Nocicptive Transmission using Indomethacin, Brain Research 739:104-110 (1996).
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Stedman's Medical Dictionary, 27th Edition, definition of Chronic.
http://atoz.iqhealth.com, Chronic Pain.
Priest & Hoggart, Chronic Pain: Mechanisms and Treatment, Current Opinion in Pharmacology, 2:310-315 (2002).
Burkey et al., “Dopamine reuptake inhibition in the rostral agranular insular cortex produces antinociception”, The Journal of Neuroscience, May 15, 1999, vol. 19, No. 10, pp. 4169-4179.

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