Method for detection of an analyte using acridinium esters and l

Details Method for detection of an analyte using acridinium esters and l Method for detection of an analyte using acridinium esters and l

1993-03-17

1995-09-12

Parr, Margaret

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Coated or structually defined flake, particle, cell, strand,...

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436829, 436528, 546102, 546104, 546107, 264 41, B32B 902

Patent

active

054495563

ABSTRACT:
A method for the detection of an analyte in a fluid sample using liposomes encapsulating acridinium esters (lumisomes). Hydrophilic polysubstituted aryl acridinium esters are useful as chemiluminescent markers and can be encapsulated within liposome vesicles without significant leakage of the esters from the vesicles. The lumisomes can be coupled to molecules with biological activity, such as antigens, antibodies, and nucleic acids, and used in luminescent assays.

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