Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Peptides containing saccharide radicals – e.g. – bleomycins – etc.
Reexamination Certificate
2003-11-11
2008-12-09
Heard, Thomas S (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Peptides containing saccharide radicals, e.g., bleomycins, etc.
Reexamination Certificate
active
07462687
ABSTRACT:
Vancomycin-polymer conjugates are disclosed. In preferred aspects, polymer residues which are hydrolysis resistant in vitro, are selectively attached to the sugar amino and/or N-methyl amino groups of vancomycin and related compounds. Vancomycin-polymer conjugates made by the methods and methods of treatment using the conjugates are also disclosed.
REFERENCES:
patent: 5681811 (1997-10-01), Ekwuribe
patent: 6180095 (2001-01-01), Greenwald et al.
patent: 2002/0103259 (2002-08-01), Martinez et al.
patent: WO 97/04796 (1997-02-01), None
patent: WO 03/040211 (2003-05-01), None
Greenwald Richard B.
Zhao Hong
Enzon Pharmaceuticals, Inc.
Heard Thomas S
Lucas & Mercanti LLP
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