Alkyne compounds with MCH antagonistic activity and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C546S276400

Reexamination Certificate

active

07452911

ABSTRACT:
The present invention relates to alkyne compounds of general formula Iwherein the groups and residues A, B, W, X, Y, Z, R1and R2have the meanings given in claim1. The invention further relates to pharmaceutical compositions containing at least one alkyne according to the invention. In view of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.

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