Dioxolane intermediates

Details Dioxolane intermediates Dioxolane intermediates

1997-10-23

1999-06-15

Jones, Dwayne C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549295, C07D31700

Patent

active

059123605

ABSTRACT:
The present invention relates to intermediates, useful for the preparation of therapeutically active hydroxamic acid derivatives which are inhibitors of metalloproteinases involved in tissue degradation, and are inhibitors of the release of tumour necrosis factor from cells.

REFERENCES:
patent: 4824970 (1989-04-01), Castaldi et al.
patent: 4845243 (1989-07-01), Giordano et al.
patent: 5004832 (1991-04-01), Castaldi et al.
Calderari et al., "Asymmetric Michael Additions. Stereoselective alkylation of chiral, non-racemic enolates by nitro olefins. Preparation of enatiomerically pure gamma-aminobutyric and succinic acid derivatives", Helv. Chim. Acta 68(6), pp. 1592-1604 and 1985.

Affiliated with

Also associated with

Rating

Dioxolane intermediates does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dioxolane intermediates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dioxolane intermediates will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-403519