Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-04-01
2008-12-09
Rao, Deepak (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S269000, C514S275000, C544S315000, C544S330000, C544S331000, C544S333000, C544S334000
Reexamination Certificate
active
07462619
ABSTRACT:
In accordance with the present invention, there is provided a novel class of heterocyclic compounds. Compounds of the invention contain a substituted or unsubstituted six membered heterocyclic ring that includes at least two nitrogen atoms. The ring additionally includes four carbon atoms. The heterocyclic ring has at least one substituent located at a ring position adjacent to a ring nitrogen atom. This mandatory substituent of the ring includes a moiety (B), linked to the heterocyclic ring via a carbon-carbon triple bond. The mandatory substituent is positioned adjacent to the ring nitrogen atom. Invention compounds are capable of a wide variety of uses. For example heterocyclic compounds can act to modulate physiological processes by functioning as agonists and antagonists of receptors in the nervous system. Invention compounds may also act as insecticides, and as fungicides. Pharmaceutical compositions containing invention compounds also have wide utility.
REFERENCES:
patent: 4990520 (1991-02-01), Trybulski et al.
patent: 6774138 (2004-08-01), Cosford et al.
patent: 2003/0045524 (2003-03-01), Woodward et al.
patent: 2005/0043307 (2005-02-01), Cosford et al.
patent: 2005/0085523 (2005-04-01), Cosford et al.
patent: WO 01/16121 (2003-07-01), None
Shibata et al., Caplus Abstract 130:311757 (1999).
Wong et al., A New Series of Pyrimidine-containing Linear Molecules, Journal of Organic Chemistry, 69(23), pp. 8038-8044 (2004).
M. Varney et al., Brit. J. Pharmacology, 126 (Supp.):248 (1999)
F. Gasparini et al., Brit. J. Pharamacology, 126 (Supp.): 249 (1999).
C. Shih et al., J. Med. Chem., 35:1109-1116 (1992).
M. Varney et al., J. Med. Chem., 40:2502-2524 (1997).
M. Varney et al., J. Pharmacology and Exptl. Therapeutics, 290:170-181 (1999).
Cosford Nicholas D.
Huang Dehua
Roppe Jeffrey R.
Seiders Thomas J.
Smith Nicholas D.
Krovatin William
Merck & Co. , Inc.
Rao Deepak
Thies J. Eric
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