Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-09-03
1987-08-11
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 62, 546 81, 546 82, 546 83, 546 89, 546 95, 546 80, 546 94, C07D491497, C07D49514, A61K 3138, A61K 31435
Patent
active
046862269
ABSTRACT:
Substituted hexahydro arylquinolizines and pharmaceutically acceptable salts thereof are selective .alpha..sub.2 -adrenergic receptor antagonists and thereby useful as antidepressants, antihypertensives, ocular antihypertensives, antidiabetics, antiobesity and platelet aggregation inhibitors and modifiers of gastrointestinal motility.
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patent: 3132147 (1964-05-01), Schopf et al.
patent: 4454139 (1984-06-01), Ward et al.
patent: 4481200 (1984-11-01), Ward et al.
Szantay et al., Chem. Abstracts, vol. 96 (1982), entry 6605e.
Baldwin John J.
Guare, Jr. James P.
Huff Joel R.
Sakurai Yojiro
Vacca Joseph P.
Merck & Co. , Inc.
Nicholson William H.
Rizzo Nicholas S.
Sudol Michael C.
Teoli, Jr. William A.
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