Topical fluoroquinolone antibiotics combined with benzoyl peroxi

Details Topical fluoroquinolone antibiotics combined with benzoyl peroxi Topical fluoroquinolone antibiotics combined with benzoyl peroxi

1998-02-27

1999-06-15

Weddington, Kevin E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142305, 514252, 514315, 514468, 514481, 514859, 514714, A61K 3147, A61K 31535, A61K 31495, A61K 3134

Patent

active

059122552

ABSTRACT:
A pharmaceutical composition of all fluoroquinolones, including but not limited to, ciprofloxacin, ofloxacin, enoxacin, cinoxacin, pefloxacin, lomefloxacin, norfloxacin, tosufloxacin, fleroxacin, temafloxacin, trovafloxacin, and difloxacin, mixed with benzoyl peroxide in a vehicle for the topical treatment of a variety of skin conditions. The topical antibiotic and peeling agent will be in the form of a cream, ointment, lotion, gel, suspension, emulsion, cleansing bar, pledget, salve, tincture, spray, transdermal device, or other appropriate non-toxic pharmaceutical carrier.

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Nishijima et al. J. Dermatol., 21(3), 166-71 (Abstract), 1994.
Vogt et al. Drugs, 49 (Suppl. 2), 266-8 (Abstract), 1995.

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