Method of synthesis of desulfated heparin and use thereof for in

Details Method of synthesis of desulfated heparin and use thereof for in Method of synthesis of desulfated heparin and use thereof for in

1997-05-29

1999-06-15

Lilling, Herbert J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 21, A01N 4304, C08B 3710, A61K 31425

Patent

active

059122374

ABSTRACT:
A method and medicament for the inhibition of neutrophil elastase and cathepsin G in mammals comprising administering a treatment effective amount of 2-O-desulfated heparin to a mammal in need thereof. The medicament preferably is administered by aerosolization or by intravenous (IV) injection. Preferably, the 2-O-desulfated heparin medicament includes a physiologically acceptable carrier which may be selected from the group consisting of physiologically buffered saline, normal saline, and distilled water. Additionally provided is a method of synthesizing 2-O-desulfated heparin.

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