Substituted thienyl and furyl acylguanidines and methods of...

Details Substituted thienyl and furyl acylguanidines and methods of... Substituted thienyl and furyl acylguanidines and methods of...

2006-02-13

2008-12-02

Saeed, Kamal (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S430000

Reexamination Certificate

active

07459567

ABSTRACT:
The present invention provides a substituted thienyl or furyl acylguanidine compound of formula IThe present invention also provides methods for the inhibition of β-secretase (BACE) and for the treatment of β-amyloid deposits and neurofibrillary tangles.

REFERENCES:
patent: 0 861 831 (1998-09-01), None
patent: 2 013 192 (1979-08-01), None
MayoClinic.com, Alzheimer's disease: Cause (1 page).
Vandana et al., Journal of drug targeting (2005), vol. 13, abstract.
Su et al.; Expert opinion on drug delivery (May 2006) vol. 3, abstract.
Lefrance-Jullien et al., British Journal of Pharmacology (2005), 145, 228-235.
Fact Sheet, Alzheimer's Association, 2006.
Abbott et al., Molecular Medicine Today (1996), vol. 2, p. 106-113.

Affiliated with

Also associated with

Rating

Substituted thienyl and furyl acylguanidines and methods of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted thienyl and furyl acylguanidines and methods of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted thienyl and furyl acylguanidines and methods of... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4021619