Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1984-05-14
1987-08-11
Griffin, Ronald W.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
424438, 514 12, 435177, 435182, 604891, A61K 944, A01N 2510, C12N 1102, C12N 1104
Patent
active
046860983
ABSTRACT:
Recombinant DNA constructs having an avian retroviral long terminal repeat (LTR) ligated to the bovine growth hormone gene, were co-transformed into a mammalian cell (mouse) culture in order to obtain a stable cell culture secreting large amounts of bovine growth hormone. The transformed mouse cells were encapsulated in hollow fibers and implanted into animals, thereby producing circulating bovine growth hormone.
REFERENCES:
patent: 4391909 (1983-07-01), Lim
Hymer et al., Neuroendocrinology, 32:339-349 (1981).
Woychik et al., Nucleic Acids Research, 10:7197-7210 (1982).
Kopchick John J.
Leung Frederick C.
Livelli Thomas J.
Malavarca Richard H.
Griffin Ronald W.
Merck & Co. , Inc.
Perrella Donald J.
Pfeiffer Hesna J.
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