Process for preparation of bisphosphonic acid compounds

Details Process for preparation of bisphosphonic acid compounds Process for preparation of bisphosphonic acid compounds

2004-08-10

2008-08-12

O'Sullivan, Peter G (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus acids or salts thereof

C546S022000, C546S023000, C548S119000

Reexamination Certificate

active

07411087

ABSTRACT:
The present invention provides a novel process for preparation of bisphosphonic acids or salts thereof, e.g. alendronic acid, by reacting a carboxylic acid, phosphorous acid and a halophosphorous compound in a water miscible neutral solvent.

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