Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-01-24
2008-10-28
Berch, Mark L (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S264100, C514S264110, C514S300000, C514S309000, C514S310000, C514S311000, C514S312000, C514S313000, C514S253050, C544S058200, C544S058600, C544S128000, C544S125000, C544S126000, C544S250000, C544S279000, C544S363000, C546S090000, C546S123000, C546S141000, C546S146000, C546S156000, C546S165000, C546S122000, C546S070000
Reexamination Certificate
active
07442710
ABSTRACT:
The present invention relates to compounds of general formula IA or IBwhereinX1and X2are each independently N or C—R″ andR1, R2,R3, R4,R5, and R6are as defined in the specification and to pharmaceutically acceptable acid addition salts thereof. The compounds can be used for the treatment of diseases related to the glycine transporter inhibitor, such as schizophrenia and Alzheimer's disease.
REFERENCES:
patent: 3933802 (1976-01-01), Ferrini et al.
patent: 4244871 (1981-01-01), Kosary et al.
patent: 6001854 (1999-12-01), Ognyanov et al.
patent: 2005/0059668 (2005-03-01), Alberati-Giani et al.
patent: 2005/0070539 (2005-03-01), Alberati-Giani et al.
patent: 2005/0209241 (2005-09-01), Jolidon et al.
patent: 2006/0287308 (2006-12-01), Bird et al.
patent: 2007/0197565 (2007-08-01), Kelly et al.
patent: 2007/0197587 (2007-08-01), Ali Awad et al.
patent: 2007/0203179 (2007-08-01), Clark et al.
patent: 0 171 636 (1985-02-01), None
patent: 0 624 584 (1994-11-01), None
patent: WO 99/44596 (1999-09-01), None
patent: WO 99/45011 (1999-09-01), None
patent: WO 01/81308 (2001-11-01), None
patent: WO 02/22581 (2002-03-01), None
patent: WO 02/22612 (2002-03-01), None
patent: WO 03/004480 (2003-01-01), None
patent: WO 03/035602 (2003-05-01), None
patent: WO 2004/037800 (2004-05-01), None
patent: WO 2004/113301 (2004-12-01), None
patent: WO 2005/058882 (2005-06-01), None
patent: WO 2005/110983 (2005-11-01), None
U.S. Appl. No. 10/911,359, filed Aug. 4, 2004, pending.
U.S. Appl. No. 10/933,103, filed Sep. 2, 2004, pending.
U.S. Appl. No. 10/933,072, filed Sep. 1, 2004, pending.
U.S. Appl. No. 11/291,216, filed Dec. 1, 2005, pending.
U.S. Appl. No. 11/324,990, filed Jan. 3, 2006, pending.
U.S. Appl. No. 11/297,597, filed Dec. 8, 2005, pending.
U.S. Appl. No. 11/302,403, filed Dec. 13, 2005, pending.
U.S. Appl. No. 11/324,991, filed Dec. 3, 2006, pending.
U.S. Appl. No. 11/332,999, filed Jan. 17, 2006, pending.
Lewis D.A. & Lieberman J.A., Neuron. vol. 28, pp. 325-334 (2000).
Vandenberg R. J. & Aubrey K. R., Exp. Opin. Ther. Targets vol. 5(4) pp. 507-518 (2001).
Nakazato A. & Okuyama S., Exp. Opin. Ther. Patents vol. 10(1) pp. 75-98 (2000).
Sharma T., Br. J. Psychiatry, vol. 174 (Suppl. 38) pp. 44-51 (1999).
Javitt D. C. et al., Biol. Psychiatry, vol. 45 pp. 668-679 (1999).
Mohn A. R., et al., Cell, vol. 98 pp. 427-436 (1999).
Bliss, T. V. & Collingridge G. L., Nature, vol. 361 pp. 31-39 (1993).
Tang J. P. et al., Nature, vol. 401, pp. 63-69 (1999).
Gainetdinov R. R. et al., Trends in Pharm. Sci. vol. 23(8) pp. 367-373 (2002).
Lopez-Corcuera B, et al., Mol. Mem. Biol. vol. 18 pp. 13-20 (2001).
Bergeron R. et al., Proc. Natl. Acad. Sci. USA vol. 95, pp. 15730-15734 (1998).
Chen et al., J. Neurophysiol. vol. 89(2) pp. 691-703 (2003).
Armer R. E. & Miller D. J., Exp. Opin. Ther. Patents vol. 11(4) pp. 563-572 (2001).
Pralong E. et al., Prog. in Neurobiol. vol. 67, pp. 173-202 (2002).
Carlsson M. L., J. Neural Trans. vol. 105, pp. 525-535 (1998).
Kwong et al., Org. Lett. 4, pp. 581-584 (2002).
Kuwano et al., JOC 67, pp. 6479-6486 (2002).
Chem. Abstract XP-002299148.
Caulfield W. L. et al., Journal of Med. Chem. vol. 44(17) pp. 2679-2682 (2001).
Chem. Abstract XP-002299149.
Chemical Abstracts Service, Apr. 23, 2003, XP002308402, Database accession No. 2003: 2142911 Chemcats & Catalog: AsInExExpress Gold.
Chemical Abstracts Service, Jun. 6, 2003, XP002308481 & Database Chemcats.
Chemical Abstracts Service, Jan. 1, 2004, XP002308405, Database accession No. 2003:2872406 Chemcats & Catalog: Ambinter Stock Screening Collection.
Chemical Abstracts Service, Jan. 1, 2004, XP002308403, Database accession No. 2004:591813 & Catalog: Ambinter Stock Screening Collection.
Chemical Abstracts Service, Jan. 1, 2004, XP002308404, Database accession No. 2004:660630 & Catalog: Ambinter Screening Library.
Chemical Abstracts Service, XP002308978.
Chemical Abstracts Service, XP002308979; Chemcats No. 2003:1026314.
Chemical Abstracts Service, XP002308980; Chemcats No. 2001;2814605.
Chemical Abstracts Service, XP002308981; Chemcats No. 2002:2063001.
Chemical Abstracts Service, XP002308983; Chemcats No. 2003:1026533.
Chemical Abstracts Service, XP002308984; Chemcats No. 2002:2288893.
Chemical Abstracts Service, XP002308985; Chemcats No. 2003:709504.
Chemical Abstracts Service, XP002308986; Chemcats No. 2003:709503.
Chemical Abstracts Service, XP002308987; Chemcats No. 2003:709505.
Chemical Abstracts Service, XP002308988; Chemcats No. 2004:1498769.
Chemical Abstracts Service, XP002308989; Chemcats No. 2002:2386068.
Chemical Abstracts Service, XP002308990; Chemcats No. 2002:2894607.
Chemical Abstracts Service, XP002308991; Chemcats No. 2003:3342164.
Chemical Abstracts Service, XP002308992; Chemcats No. 2003:3345505.
Chemical Abstracts Service, XP002308993; Chemcats No. 2003:3346187.
Chemical Abstracts Service, XP002309007; Chemcats No. 2004:660630.
Abstract corresponding to Document B5—WO 03/035602.
Cabiddu et al., Journal of Organometallic Chemistry, 1991, 419(1-2) 1-8.
Collins, et al., J. Med. Chem. 1998, 41, p. 5037-5054.
Yamanaka et al., Tetrahedron Lett., 1996, vol. 37, p. 1829-1832.
Guisado et al., Tetrahedron Lett., 2002, vol. 43, p. 7105-7109.
Souers et al., Bioorganic & Medicinal Chem. Letters, vol. 14(19) pp. 4883-4886 (2004).
Wolin et al., Bioorganic & Medicinal Chem. vol. 12, pp. 4511-4532 (2004).
Lowe, John A., III, Expert Opin. Ther. Patents vol. 15 (11) pp. 1657-1662 (2005).
Jolidon Synese
Narquizian Robert
Norcross Roger David
Pinard Emmanuel
Berch Mark L
Hoffman-La Roche Inc.
Jaisle Cecilia M
Johnston George W.
Prior Kimberly J.
LandOfFree
Substituted phenyl methanones does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted phenyl methanones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted phenyl methanones will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4016431