Multimode ion source with improved ionization

Details Multimode ion source with improved ionization Multimode ion source with improved ionization

2005-12-20

2008-08-12

Berman, Jack I. (Department: 2881)

Radiant energy

Ionic separation or analysis

With sample supply means

C250S42300F, C250S42300F, C250S424000, C250S425000, C250S427000, C250S281000, C250S282000

Reexamination Certificate

active

07411186

ABSTRACT:
A multimode ionization source with improved ionization characteristics that comprises an electrospray ionization source for providing a charged aerosol, an atmospheric pressure chemical ionization (APCI) source including a corona needle having an end positioned downstream from the electrospray ionization source for producing a discharge that further ionizes the charged aerosol, an assist gas inlet positioned adjacent to the corona needle for providing assist gas, the assist gas facilitating ionization of the charged aerosol by the corona discharge, and a conduit having an orifice for receiving ions from the charged aerosol.

REFERENCES:
patent: 6646257 (2003-11-01), Fischer et al.
C. Perazolli et al., “Benzene-assisted atmospheric-pressure chemical ionization: a new liquid chromatography/mass spectrometry approach to the analysis of selected hydrophobic compounds”, Rapid Communications in Mass Spectrometry, (2005), vol. 19, pp. 461-469.

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