Proteins within the type E botulinum neurotoxin complex

Details Proteins within the type E botulinum neurotoxin complex Proteins within the type E botulinum neurotoxin complex

2004-01-27

2008-10-07

Kam, Chih-Min (Department: 1656)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S236100, C424S009100, C514S002600, C514S012200, C530S350000, C435S252700

Reexamination Certificate

active

07431935

ABSTRACT:
The invention features a polypeptide complex synthesized by bacteria of the genusClostridiathat contains the serotype Ebotulinumneurotoxin and five neurotoxin associated polypeptides having molecular weights of about 118, 80, 65, 40, and 18 kDa. respectively. The complex is useful in the treatment of diseases or conditions that are caused by excessive release of acetylcholine from presynaptic nerve terminals.

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