Human T2R receptors for acetaminophen ranitidine, strychnine...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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Details

C435S007200, C435S007210, C436S501000

Reexamination Certificate

active

07407765

ABSTRACT:
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter ligands, i.e., acetaminophen, ranitidine, strychnine and denatonium. The present invention further relates to the use of these receptors in assays for identifying ligands that modulate the activation of these taste receptors and which may be used as additives in foods, beverages and medicinals for modifying (blocking) T2R-associated bitter taste.

REFERENCES:
patent: 7022488 (2006-04-01), Servant et al.
patent: 7105650 (2006-09-01), Adler

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