Method of inducing an immune response in a young animal

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424423, 424426, 4241841, 4242041, 4242061, 4242111, 4242161, 4242341, 4242431, 4242441, 4242471, 4242521, 4242571, 4242581, 4242591, 4242601, 4242741, A61K 3902, A61K 3912, A61K 3900

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active

059068264

ABSTRACT:
The invention provides a method of priming an immune response in the presence of maternal antibody in a young animal by administering to a 1-90 day old animal, a biocompatible and non-toxic solid phase implant containing an immunogenic agent. A preferred implant according to the invention is one that becomes gradually disintegrated in situ the animal. The implant provides for extended sustained delivery of the immunogenic agent into surrounding tissue fluids in the presence of circulating maternal antibodies to provide a priming dose of the immunogenic agent to stimulate substantially immediate antibody production for active immunity against a pathogen when passive protection is no longer provided by circulating maternal antibodies.

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