Composite hydrogel drug delivery systems

Details Composite hydrogel drug delivery systems Composite hydrogel drug delivery systems

2003-08-12

2008-08-19

Dodson, Shelley A. (Department: 1616)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S486000, C424S487000

Reexamination Certificate

active

07413752

ABSTRACT:
Compositions and methods are provided to control the release of relatively low molecular weight therapeutic species through hydrogels by first dispersing or dissolving such therapeutic species within relatively hydrophobic rate modifying agents to form a mixture. The mixture is formed into microparticles that are dispersed within bioabsorbable hydrogels, so as to release the water soluble therapeutic agents in a controlled fashion. Methods of using the compositions of the present invention in therapeutic systems are also provided.

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