Isoelectric particles and uses thereof

Details Isoelectric particles and uses thereof Isoelectric particles and uses thereof

2004-05-07

2008-08-05

Lam, Ann Y (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

C436S528000

Reexamination Certificate

active

07407816

ABSTRACT:
A plurality of particles of from about 5 nm to 100 μm possessing predetermined isoelectric points in the pH range from about 2.5 to 11 is used in a method of detection of a plurality of analytes, wherein the isoelectric particles of each isoelectric point further contain a label and a member of a binding pair capable of interacting with a selected analyte. The particles that formed specific binding pairs are recovered and separated by isoelectric focusing, followed by the detection of the labels associated with the particles. A flow cytometer may be used as a detector of the isoelectric particles.

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