Microfiltration membranes having high pore density and mixed iso

Liquid purification or separation – Filter – Material

Patent

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Details

210490, 21050022, 21050027, 2103216, 264 41, 264 49, B01D 3900

Patent

active

059067420

ABSTRACT:
The present invention relates to the field synthetic polymeric microfiltration membrane materials that are fabricated to separate liquids from solids contained therein. One aspect of the invention relates to a sulfone polymer membrane with high surface porosity (high pore density) and distinctive asymmetry that can separate solids (i.e., blood cells) from a liquid (i.e., plasma) without the need for centrifugation. The membrane is further rendered hydrophilic through co-casting the sulfone polymer (which is a hydrophobic polymer) with a hydrophilic polymer, such as polyvinylpyrrolidone. Because of these properties and the fact that it requires only a small amount of the solid containing liquid (i.e., whole blood) to be applied to the larger pore surface, the membranes of the invention are highly useful in testing devices for the quick detection of properties or components contained in liquid samples, such as diagnostic applications (i.e., the detection of physiological conditions (i.e., pregnancy, insulin levels, stomach ulcer, and the like) and infectious diseases (i.e., AIDS, hepatitis, and the like)).

REFERENCES:
patent: 4840733 (1989-06-01), Sasaki et al.
patent: 5846422 (1998-12-01), Ditter et al.

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