Porous bioceramics for bone scaffold and method for...

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone

Reexamination Certificate

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C427S002270

Reexamination Certificate

active

07416564

ABSTRACT:
The present invention provides a porous bioceramics for bone scaffold. The porous bioceramics according to the present invention comprises a biocompatible porous ceramic substrate having the property to thermal-decompose hydroxyapatite in contact with it; a fluorapatite (FA) inner layer formed on said porous ceramic substrate; and a hydroxyapatite (HA) outer layer formed on said fluorapatite inner layer. The insertion of FA intermediate layer can prevent the thermal reaction between ZrO2and HA. Therefore, the present invention can provide the implant material into human body having excellent mechanical properties of zirconia as well as the biocompatibility, bioaffinity and bioactivity of HA. The present invention can also provide the implant material to promote osteoconduction and osteointegration in human body.

REFERENCES:
patent: 2003/0099762 (2003-05-01), Zhang et al.
patent: 2000-2933 (2000-01-01), None
patent: 2000-18897 (2000-04-01), None
Authors Hae-Won Kim, Yoon-Jung Noh, Young,-Hag Koh, Hyoun-Ee Kim and Hyun-Man Kim; Title: Effect of CaF2on densification and properties of hydroxyapatite-zirconia composites for biomedical applications; Date: Received Dec. 12, 200—Accepted Apr. 18, 2002 Pertinent pp. 4113-4121.
Authors: Hae-Won Kim, Seung-Yong Lee, Chang-Jun Bae, Yoon-Jung Noh, Hyoun-Ee Kim, Hyun-Man Kim, Jea Seung Ko; Title: Porous ZrO2bone scaffold coated with hydroxyapatite with flouraplatite intermediate layer; Date: Received Nov. 10, 2002—accepted Mar. 9, 2003.

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