Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2005-08-26
2008-09-30
Tsang, Cecilia (Department: 4131)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C536S055200
Reexamination Certificate
active
07429573
ABSTRACT:
A method of treating a mammal for a purpose selected from the group consisting of (a) increasing bone mineral density (BMD), (b) treating low BMD, (c) preventing and treatment of low impact fractures, (d) treatment of high impact fractures; (e) treating osteoporosis; (f) modulating a growth factor that influences bone metabolism; and (g) improving bone micro-architecture or connectivity of bone; the method comprising administering to the mammal an effective amount of a N-acylated-2-glucosamine derivative of the general formula (I):wherein R is an alkyl radical of the general formula CnH2n+1and n is selected from 2-12; or pharmaceutically-acceptable salts, esters and glucosides thereof; or pharmaceutically-acceptable compositions thereof.
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d'Avis et al, “Age-related changes in effects of insulin-like growth factor I on human osteoblast-like cells”,J. Biochem, 1997, 324:753-760, Great Britain.
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Goon Scarlett
Manelli Denison & Selter PLLC
Melcher Jeffrey S.
Tsang Cecilia
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