Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Calorimeter
Reexamination Certificate
2004-04-30
2008-10-21
Noguerola, Alex (Department: 1795)
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Calorimeter
C257S253000, C204S403010
Reexamination Certificate
active
07438851
ABSTRACT:
A micromachined device such as a solid-state liquid chemical sensor for receiving and retaining a plurality of separate liquid droplets at desired sites, a method of making the device and a method of using the device are provided. The technique works for both aqueous and solvent-based solutions. The device includes a substrate having an upper surface, and a first set of three-dimensional, thin film well rings patterned at the upper surface of the substrate. Each of the wells is capable of receiving and retaining a known quantity of liquid at one of the desired sites through surface tension. A method for patterning a membrane/solvent solution results in reproducibly-sized, uniformly-thick membranes. The patterning precision of this method allows one to place the membranes closer together, making the sensors smaller and less expensive, and the uniform film thickness imparts reproducibility to the sensors. The final film thickness can be controlled over a 3 to 50 micron range, and lateral dimensions can be as small as 20 microns using conventional materials. The simple patterning steps can be done on full wafers in a mass fabrication process. A second set of well rings may be photo-patterned at the same time as the first set of well rings to isolate functional groups on top of ion-selective membrane.
REFERENCES:
patent: 4874499 (1989-10-01), Smith et al.
patent: 4975175 (1990-12-01), Karube et al.
patent: 5200051 (1993-04-01), Cozzette et al.
patent: 5334837 (1994-08-01), Ikeda et al.
patent: 5376255 (1994-12-01), Gumbrecht et al.
patent: 5393401 (1995-02-01), Knoll
patent: 5403462 (1995-04-01), Lev et al.
patent: 5955352 (1999-09-01), Inoue et al.
patent: 6251567 (2001-06-01), Reinecke et al.
patent: 6440296 (2002-08-01), Stanzel et al.
patent: 6766817 (2004-07-01), da Silva
patent: 197 05 910 (1998-06-01), None
patent: 1 053 784 (2000-11-01), None
patent: 1 193 495 (2002-04-01), None
patent: WO 98/09160 (1998-03-01), None
patent: WO 98/13675 (1998-04-01), None
patent: WO 99/39829 (1999-08-01), None
patent: WO 00/67293 (2000-11-01), None
patent: WO 01/07161 (2001-02-01), None
patent: WO 01/83674 (2001-11-01), None
patent: WO 02/41996 (2002-05-01), None
Table 1 on p. 15 in Handbook of Thin-Film Deposition Processes and Techniques—Principles, Methods, Equipment and Applications (2nd edition) edited by K. Seshan, 2002.
Hower, R.W., et al., New Solvent System For the Improved Electrochemical Performance of Screen-Printed Polyruethane Membrane-Based Solid-State Sensors, Proceedings For Transducers 95/Eurosensors IX, Jun. 1995, pp. 858-862.
Anna S., et al., An IC-Technology Compatible Automatic Method (SCZ Method) For Immobilization Membranes, vol. B1, pp. 514-517, 1990.
Bousse, L.J., et al., Silicon Micromachining in the Fabrication of Biosensors Using Living Cells, Technical Digest, IEEE Solid-State Sensor and Actuator Workshop, Hilton Head, S.C., pp. 173-176, Jun. 1990.
Eugster, R., et al., Selectivity-Modifying Influence of Anionic Sites in Neutral-Carrier-Based Membrane Electrodes, Analytical Chemistry, vol. 63, pp. 2285-2289, 1991.
Hower, R.W., et al., Study of Screen-Printed Wells in Solid-State Ion Selective Electrodes, Technical Digest, IEEE Solid-State Sensor and Actuator Workshop, Hilton Head Island, S.C., 1996.
Hjelt, Kari T., et al., Measuring Liquid Evaporation From Micromachined Wells, Sensors and Actuators 85, 2000, pp. 384-389.
Ramsey, J.Michael, et al., Microfabricated Chemical Measurement Systems, Nature Medicine, vol. 1, No. 10, Oct. 1995, pp. 1093-1096.
Brown Richard B.
Hower Robert W.
Brooks & Kushman P.C.
Noguerola Alex
The Regents of the University of Michigan
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