Spiro-piperidine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C544S071000

Reexamination Certificate

active

07432259

ABSTRACT:
Present invention is concerned with novel indol-2-yl-carbonyl-spiro-piperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them. The active compounds of the present invention are useful in the treatment of anxiety and depressive disorders and other diseases. The compounds of present invention have the general formula (I)wherein R1to R11and X are as defined in the description.

REFERENCES:
patent: WO 00/14067 (2000-03-01), None
patent: WO 01/85725 (2001-11-01), None
patent: WO 2004/035549 (2004-04-01), None
patent: WO 2007/077122 (2007-07-01), None
Ebner et al., (2002), Eur. J. Neurosci. vol. 15 pp. 384-388.
Bielsky et al., (2004), Neuropsychopharmacology, vol. 29 pp. 483-493.
Michelini et al., (1999), Annals NY Acad. Sci. vol. 897 pp. 198-211.
Van Kerckhoven et al., (2002) Eur. J. Pharmacol. vol. 449 pp. 135-141.
Liebsch et al., (1995), Regulatory Peptides vol. 59 pp. 229-239.
Clark, R. et al,Jour of Med. Chem. (1983) XP002432972.
Clark, R. et al,Jour of Med. Chem. (1995) XP000941460.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Spiro-piperidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Spiro-piperidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Spiro-piperidine derivatives will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3991955

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.