Method of employing elevation of marinobufagenin in...

Details Method of employing elevation of marinobufagenin in... Method of employing elevation of marinobufagenin in...

2004-02-02

2008-10-21

Wallenhorst, Maureen M (Department: 1797)

Chemistry: analytical and immunological testing

Peptide, protein or amino acid

Glycoproteins

C436S063000, C436S065000

Reexamination Certificate

active

07439071

ABSTRACT:
A method of determining the presence of preeclampsia is provided wherein a determination is made as to whether there has been a substantial elevation in marinobufagenin which may be a blood-derived or urine-derived and if such elevation does exist concluding that preeclampsia does exist in a patient. The method may advantageously be practiced by employing urine, blood serum or blood plasma as the body specimen containing the protein in determining whether a patient has preeclampsia. The method may include subsequent therapeutic patient treatment. Related diagnostic apparatus is also provided.

REFERENCES:
patent: 5079171 (1992-01-01), Senyei et al.
patent: 5543138 (1996-08-01), Keith
patent: 5770376 (1998-06-01), Bagrov
patent: 2003/0044856 (2003-03-01), Puschett
patent: 2006/0134106 (2006-06-01), Adair
Bagrov, Alexei Y., et al., “Characterization of a Urinary Bufodienolide Na+, K+-ATPase inhibitor in Patients After Acute Myocardial Infarction,” Hypertension, vol. 31, No. 5, pp. 1097-1103, May 1998.
Chen, Tai C., et al., “Volume Expansion-Induced Changes in Renal Tubular Membrance Protein Phosphorylation,” Biochemical and Biophysical research Communications, vol. 143, No. 1, pp. 74-80, Feb. 1987.
Lopatin, D.A. et al., “Circulating Bufodienolide and Cardenolide Sodium Pump Inhibitors in Preeclampsia,” Journal of Hypertension, 1999, vol. 17, No. 8, pp. 1179-1187.
Khedun, S.M. et al., “Drug Management of Hypertensive Disorders or Pregnancy,” Pharmacol. Ther., 1997, vol. 74, No. 2, pp. 221-258.

Affiliated with

Also associated with

Rating

Method of employing elevation of marinobufagenin in... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of employing elevation of marinobufagenin in..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of employing elevation of marinobufagenin in... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3990414